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CAS : 959-14-8 ProductName : Oxolamine
MSDS  :
 1,2,4-Oxadiazole, 5-(2-(diethylamino)ethyl)-3-phenyl-
CAS  
:
 959-14-8
SYNONYMS  
:
 * AF 438
* 5-(2-Diethylaminoethyl)-3-phenyl-1,2,4-oxadiazole
* N,N-Diethyl-3-phenyl-1,2,4-oxadiazole-5-ethanamine
* 5-(2-(Diethylamino)ethyl)-3-phenyl-1,2,4-oxadiazole
* 5-(2-Dietilaminoetil)-3-fenil-1,2,4-oxadiazolo
* 683 M
* Oxolamina
* Oxolamine
* 3-Phenyl-5-(beta-diethylaminoethyl)-1,2,4-oxodiazole

Catalog of Chemical Suppliers, Buyers, Custom Synthesis Companies And Equipment Manufacturers
[ 1,2,4-Oxadiazole, 5-(2-(diethylamino)ethyl)-3-phenyl- 959-14-8 ]
                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RO0700000
CHEMICAL NAME           : 1,2,4-Oxadiazole, 5-(2-(diethylamino)ethyl)-3-phenyl-
CAS REGISTRY NUMBER     : 959-14-8
BEILSTEIN REFERENCE NO. : 0527181
LAST UPDATED            : 199612
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C14-H19-N3-O
MOLECULAR WEIGHT        : 245.36
WISWESSER LINE NOTATION : T5NO DNJ C2N2&2 ER
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * AF 438
   * 5-(2-Diethylaminoethyl)-3-phenyl-1,2,4-oxadiazole
   * N,N-Diethyl-3-phenyl-1,2,4-oxadiazole-5-ethanamine
   * 5-(2-(Diethylamino)ethyl)-3-phenyl-1,2,4-oxadiazole
   * 5-(2-Dietilaminoetil)-3-fenil-1,2,4-oxadiazolo
   * 683 M
   * Oxolamina
   * Oxolamine
   * 3-Phenyl-5-(beta-diethylaminoethyl)-1,2,4-oxodiazole
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   103,115,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 679 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   103,115,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 208 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PMDCAY Progress in Medical Chemistry.  (Elsevier Science Pub. Co., Inc., 52
   Vanderbilt Ave., New York, NY 10017)  V.1-    1961- Volume(issue)/page/year:
   3,89,1963
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 672 mg/kg
TOXIC EFFECTS :
   Behavioral - analgesia
   Nutritional and Gross Metabolic - body temperature decrease
   Biochemical - Metabolism (Intermediary) - effect on inflammation or
   mediation of inflammation
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 10,411,1967

                              *** REVIEWS ***
 
   TOXICOLOGY REVIEW
   ADCSAJ Advances in Chemistry Series.  (American Chemical Soc., Distribution
   Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037)  No.1-
   1950-  Volume(issue)/page/year: 13,271,1970

 
                            *** END OF RECORD ***

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