Guanosine, 2'-deoxy-

CAS  

 961-07-9

SYNONYMS  

 * Deoxyguanosine
* 2'-Deoxyguanosine
* Guanine deoxyriboside

                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MF8760000
CHEMICAL NAME           : Guanosine, 2'-deoxy-
CAS REGISTRY NUMBER     : 961-07-9
LAST UPDATED            : 199701
DATA ITEMS CITED        : 8
MOLECULAR FORMULA       : C10-H13-N5-O4
MOLECULAR WEIGHT        : 267.28
WISWESSER LINE NOTATION : T56 BN DN FMYMVJ GUM D- ET5OTJ B1Q CQ
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Deoxyguanosine
   * 2'-Deoxyguanosine
   * Guanine deoxyriboside
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ADTEAS Advances in Teratology.  (New York, NY)  V.1-5, 1966-72.
   Discontinued.  Volume(issue)/page/year: 3,181,1968
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 1 mmol/L
REFERENCE :
   BICMBE Biochimie.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.53-    1971-
   Volume(issue)/page/year: 64,809,1982
 
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Fibroblast
DOSE/DURATION           : 500 umol/L
REFERENCE :
   CYTOAN Cytologia.  (Japan Pub. Trading Co. (USA), 1255 Howard St., San
   Francisco, CA 94103) V.1-    1929-  Volume(issue)/page/year: 49,667,1984
 
TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Fibroblast
DOSE/DURATION           : 500 umol/L
REFERENCE :
   CYTOAN Cytologia.  (Japan Pub. Trading Co. (USA), 1255 Howard St., San
   Francisco, CA 94103) V.1-    1929-  Volume(issue)/page/year: 49,667,1984
 
TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 1 mmol/L
REFERENCE :
   BICMBE Biochimie.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.53-    1971-
   Volume(issue)/page/year: 64,809,1982
 
TYPE OF TEST            : DNA damage
TEST SYSTEM             : Mammal - species unspecified Lymphocyte
DOSE/DURATION           : 50 mmol/L
REFERENCE :
   PNASA6 Proceedings of the National Academy of Sciences of the United States
   of America.  (National Academy of Sciences, Printing & Pub. Office, 2101
   Constitution Ave., Washington, DC 20418) V.1-    1915-
   Volume(issue)/page/year: 48,686,1962

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X1005
       No. of Facilities: 35 (estimated)
       No. of Industries: 1
       No. of Occupations: 1
       No. of Employees: 115 (estimated)
       No. of Female Employees: 64 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***