[2,2'-Binaphthalene]-8,8'-dicarboxaldehyde,1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-, (2R)- MSDS CasNo.90141-22-3

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CAS : 90141-22-3

MSDS	:	(2,2'-Binaphthalene)-8,8'-dicarboxaldehyde, 1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl- 5,5'-bis(1-methylethyl)-, (-)-
CAS	:	90141-22-3
SYNONYMS	:	* (-)-Gossypol

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[ (2,2'-Binaphthalene)-8,8'-dicarboxaldehyde,1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-, (-)- 90141-22-3 ]

                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DU3103500
CHEMICAL NAME           : (2,2'-Binaphthalene)-8,8'-dicarboxaldehyde,
                          1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-
                          5,5'-bis(1-methylethyl)-, (-)-
CAS REGISTRY NUMBER     : 90141-22-3
BEILSTEIN REFERENCE NO. : 1917878
REFERENCE               : 4-08-00-03754 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C30-H30-O8
MOLECULAR WEIGHT        : 518.60
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * (-)-Gossypol
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 210 mg/kg
SEX/DURATION            : male 2 week(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
   sperm morphology, motility, and count)
   Reproductive - Fertility - male fertility index (e.g. # males impregnating
   females per # males exposed to fertile nonpregnant females)
REFERENCE :
   JOETD7 Journal of Ethnopharmacology.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1979-  Volume(issue)/page/year:
   20,21,1987
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - hamster
DOSE                    : 320 mg/kg
SEX/DURATION            : male 40 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - male fertility index (e.g. # males impregnating
   females per # males exposed to fertile nonpregnant females)
REFERENCE :
   CCPTAY Contraception.  (Geron-X, Inc., POB 1108, Los Altos, CA 94022)  V.1-
   1970-  Volume(issue)/page/year: 31,141,1985
 
                            *** END OF RECORD ***

GOSSYPOL