CAS : 68937-83-7
Date of Issue: 9 September, 2003
MATERIAL SAFETY DATA SHEET
COMPANY DETAILS: Telephone No.: (weekdays) 09 - 306 1500
Syngenta Crop Protection Limited
Tower II, Level 7, 110 Symonds Street National Poisons & Hazchem
Private Bag 92618, Information Centre : 0800 POISON
Symonds Street (0800 764 766)
AUCKLAN NEW ZEALAND Emergency No. (24 Hours) 0800 734 607
IDENTIFICATION
TOPAS? 200 EW
PRODUCT NAME:
Formulation type: Emulsion in water Dangerous Goods Class 9
Active Ingredient: penconazole Packaging Group III
Product Code No.: CGA71818 (A-9246A) Hazchem Code: 2X
Chemical type: triazole Toxic Substances S4
Schedule:
UN Number: 3082 Marine pollutant Yes
Proper Shipping Name: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S
( CONTAINS SOLVENT NAPHTHA) MARINE POLLUTANT
USE: For the control of powdery mildew in grapes, cucurbits, peas and apples and blackspot in
apples and pears.
PHYSICAL DESCRIPTION/PROPERTIES
Appearance: White to beige milky liquid Behaviour in water: Emulsifiable
>950C
Odour: Acidic- musty Flash Point:
1.03g/cm3 (at 20??
Bulk density C) Flammability: Non-flammable
OTHER PROPERTIES
Combustibility: Combustible Volatility: Not available
Viscosity: 700--1000 mPas Corrosiveness: Non-corrosive
pH 3-7 (1% dispersion deionized Combustible Yes
water)
INGREDIENTS -
CAS No. Content (%w/v)
penconazole (technical grade) >20
to give penconazole 66246-88-6 20
aromatic petroleum hydrocarbon liquid mixture 64742-94-5 >12
Fatty acid , C6-10 , Me esters 68937-83-7 >13
HEALTH HAZARD INFORMATION
HEALTH EFFECTS
ACUTE
Toxicity - This product is slightly hazardous (WHO Hazard Class III)
Swallowed: LOW TOXICITY
Tests on rats indicate a low toxicity following single doses of the undiluted product.
(LD50 >3000 mg/kg)
Dermal LOW TOXICITY
absorption: Tests on rats indicate a low toxicity due to skin contact with the undiluted product.
(LD50 >4000 mg/kg)
Inhaled: Not available
TOPAS 200 EW
Irritation
Eye: IRRITANT (based on studies with rabbits)
Skin: IRRITANT (based on studies with rabbits)
Sensitisation Not sensitizing
Skin: Penconazole technical and the formulated product did not induce a sensitisation
reaction in guinea pigs. The sensitising potential of the hydrocarbon liquid is not
known.
CHRONIC (Active Ingredient)
Penconazole technical has been extensively tested on laboratory mammals and in test-tube systems. No
evidence of mutagenic, carcinogenic, teratogenic or reproductive effects was obtained.
The aromatic petroleum hydrocarbon liquid may cause central nervous system depression and narcosis.
FIRST AI In case of poisoning by any exposure route contact a doctor or Poisons Information Centre.
Swallowed: If poisoning occurs contact a doctor or Poisons Information Centre. If swallowed DO NOT
induce vomiting. Give a glass of water. Begin artificial respiration if victim is not breathing.
Use mouth to nose rather than mouth to mouth. Take to hospital without delay.
Eye: Flush with large quantities of clean tap water for at least 15 minutes. Call a doctor
Skin: Remove contaminated clothing and wash affected areas thoroughly with soap and water.
Inhaled: Move affected person to fresh air and keep at rest until recovered. Call a doctor
ADVICE TO DOCTO No specific antidote is available. If poisoning is suspected apply symptomatic therapy.
PRECAUTIONS FOR USE
ALWAYS READ AND FOLLOW THE LABEL INSTRUCTIONS AND WARNINGS
EXPOSURE STANDARDS
No exposure standards have been set for the components of this product. The manufacturer of the liquid
aromatic hydrocarbon solvent recommends an occupational exposure limit of 100 mg/L of air (8 hour time-
weighted average).
Exposure Potential - Swallowing is unlikely under normal conditions of usage. Inhalation of spray mist is a
possible route of exposure. The aromatic hydrocarbon solvent may be absorbed through skin that comes into
direct contact with this product. This product is diluted with water prior to use as a spray. This diluted form is
less toxic by all exposure routes.
Re-entry Period - Do not enter treated areas without protective clothing until spray has dried.
ENGINEERING CONTROLS
No special requirements. Product is used outdoors.
PERSONAL PROTECTION
Avoid contact with eyes and skin. Do not inhale spray mist. When preparing the spray wear cotton overalls
buttoned to the neck and wrist, washable hat, elbow-length PVC gloves, impervious footwear and a face-shield
or goggles. If clothing becomes contaminated with product remove clothing immediately. If product gets on
skin immediately wash area with soap and water. After use and before eating, drinking or smoking, wash
hands, arms and face thoroughly with soap and water. Wear a half face-piece respirator with combined dust
and vapour cartridge if the level of the aromatic hydrocarbon solvent is likely to exceed the recommended
exposure standard given above.
FLAMMABILITY
This product is NON-FLAMMABLE. Product is combustible.
TOPAS 200 EW
SAFE HANDLING INFORMATION
STORAGE AND TRANSPORT
Store in the tightly sealed, original containers in a dry, secure, well-ventilated place away from fertilisers, seed,
feed and food. Store out of direct sunlight. Keep out of reach of children, unauthorised persons and animals.
Avoid temperatures below -5?? and above 35??
C C
SPILLS AND DISPOSAL
In case of spillage it is important to take all steps necessary to:
?? Avoid eye and skin contact.
?? Avoid contamination of waterways.
Procedure for spill:
(1) Keep all bystanders away.
(2) Wear goggles, half face-piece respirator with combined dust and vapour cartridge, full length clothing and
PVC gloves.
(3) Reposition any leaking containers so as to minimise further leakage.
(4) Dam and absorb spill with an absorbent material (e.g. sand or soil).
(5) Shovel the absorbed spill into drums.
(6) Disposal of the absorbed material will depend upon the extent of the spill.
?? For quantities up to 50 L of product bury in a secure landfill site.
?? For quantities greater than 50 L seek advice from the manufacturer (use emergency contact number
below) before attempting disposal. Contain in a secure location until disposal method is established.
(7) Decontaminate the spill area with detergent and water and rinse with the smallest volume of water
practicable
Dispose of empty, used containers by:
(a) Triple rinsing or preferably pressure rinsing containers with water. Add the rinsings to the spray tank. DO
NOT dispose of undiluted chemicals on site.
(b) If recycling, replace cap and return clean containers to recycle to designated collection point.
(c) If not recycling, break, crush or puncture and bury empty containers in a local authority landfill. If no
landfill is available, bury the containers below 500 mm in a disposal pit specifically marked and set up for
this purpose clear of waterways, desirable vegetation and tree roots.
(d) Burning of empty containers if circumstances, especially wind direction, permit is an alternative method.
FIRE/EXPLOSION HAZAR This product is non-flammable and non-explosive. Product is combustible. Extinguish warehouse and factory
fires using fine-water spray powder, carbon dioxide or foam. During a fire this product may release smoke and
hazardous decomposition products which are toxic or irritant. When fighting a major fire wear an air-supplied
respirator.
OTHER INFORMATION
Penconazole technical is practically non-toxic to birds and bees and moderately toxic to fish
[LC50 (96 h), rainbow trout = 1.7 - 4.3 mg/L].
Product is harmful to fish and daphniae. Toxic to algae.
Note: This product is a registered agricultural chemical and must therefore be used in accordance with the container label directions.
A comprehensive package of toxicological and environmental data for the active ingredients of this product has been
submitted to the Government health and environment authorities and has been evaluated by expert toxicologists and
environmental scientists.
CONTACT POINT: Business Manager - Crop Protection (09) 306 1500
24 HOURS EMERGENCY CONTACT: 0800 734 607
This Material Safety Data Sheet summarises our best knowledge of the health and safety hazard information of the product and how to
safely handle and use the product in the workplace. Each user should read this MSDS and consider the information in the context of
how the product will be handled and used in the workplace including in conjunction with other products.
If clarification or further information is needed to ensure that an appropriate risk assessment can be made, the user should contact this
company.
? Registered Trade Mark of a Syngenta Group Company.
MATERIAL SAFETY DATA SHEET
COMPANY DETAILS: Telephone No.: (weekdays) 09 - 306 1500
Syngenta Crop Protection Limited
Tower II, Level 7, 110 Symonds Street National Poisons & Hazchem
Private Bag 92618, Information Centre : 0800 POISON
Symonds Street (0800 764 766)
AUCKLAN NEW ZEALAND Emergency No. (24 Hours) 0800 734 607
IDENTIFICATION
TOPAS? 200 EW
PRODUCT NAME:
Formulation type: Emulsion in water Dangerous Goods Class 9
Active Ingredient: penconazole Packaging Group III
Product Code No.: CGA71818 (A-9246A) Hazchem Code: 2X
Chemical type: triazole Toxic Substances S4
Schedule:
UN Number: 3082 Marine pollutant Yes
Proper Shipping Name: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S
( CONTAINS SOLVENT NAPHTHA) MARINE POLLUTANT
USE: For the control of powdery mildew in grapes, cucurbits, peas and apples and blackspot in
apples and pears.
PHYSICAL DESCRIPTION/PROPERTIES
Appearance: White to beige milky liquid Behaviour in water: Emulsifiable
>950C
Odour: Acidic- musty Flash Point:
1.03g/cm3 (at 20??
Bulk density C) Flammability: Non-flammable
OTHER PROPERTIES
Combustibility: Combustible Volatility: Not available
Viscosity: 700--1000 mPas Corrosiveness: Non-corrosive
pH 3-7 (1% dispersion deionized Combustible Yes
water)
INGREDIENTS -
CAS No. Content (%w/v)
penconazole (technical grade) >20
to give penconazole 66246-88-6 20
aromatic petroleum hydrocarbon liquid mixture 64742-94-5 >12
Fatty acid , C6-10 , Me esters 68937-83-7 >13
HEALTH HAZARD INFORMATION
HEALTH EFFECTS
ACUTE
Toxicity - This product is slightly hazardous (WHO Hazard Class III)
Swallowed: LOW TOXICITY
Tests on rats indicate a low toxicity following single doses of the undiluted product.
(LD50 >3000 mg/kg)
Dermal LOW TOXICITY
absorption: Tests on rats indicate a low toxicity due to skin contact with the undiluted product.
(LD50 >4000 mg/kg)
Inhaled: Not available
TOPAS 200 EW
Irritation
Eye: IRRITANT (based on studies with rabbits)
Skin: IRRITANT (based on studies with rabbits)
Sensitisation Not sensitizing
Skin: Penconazole technical and the formulated product did not induce a sensitisation
reaction in guinea pigs. The sensitising potential of the hydrocarbon liquid is not
known.
CHRONIC (Active Ingredient)
Penconazole technical has been extensively tested on laboratory mammals and in test-tube systems. No
evidence of mutagenic, carcinogenic, teratogenic or reproductive effects was obtained.
The aromatic petroleum hydrocarbon liquid may cause central nervous system depression and narcosis.
FIRST AI In case of poisoning by any exposure route contact a doctor or Poisons Information Centre.
Swallowed: If poisoning occurs contact a doctor or Poisons Information Centre. If swallowed DO NOT
induce vomiting. Give a glass of water. Begin artificial respiration if victim is not breathing.
Use mouth to nose rather than mouth to mouth. Take to hospital without delay.
Eye: Flush with large quantities of clean tap water for at least 15 minutes. Call a doctor
Skin: Remove contaminated clothing and wash affected areas thoroughly with soap and water.
Inhaled: Move affected person to fresh air and keep at rest until recovered. Call a doctor
ADVICE TO DOCTO No specific antidote is available. If poisoning is suspected apply symptomatic therapy.
PRECAUTIONS FOR USE
ALWAYS READ AND FOLLOW THE LABEL INSTRUCTIONS AND WARNINGS
EXPOSURE STANDARDS
No exposure standards have been set for the components of this product. The manufacturer of the liquid
aromatic hydrocarbon solvent recommends an occupational exposure limit of 100 mg/L of air (8 hour time-
weighted average).
Exposure Potential - Swallowing is unlikely under normal conditions of usage. Inhalation of spray mist is a
possible route of exposure. The aromatic hydrocarbon solvent may be absorbed through skin that comes into
direct contact with this product. This product is diluted with water prior to use as a spray. This diluted form is
less toxic by all exposure routes.
Re-entry Period - Do not enter treated areas without protective clothing until spray has dried.
ENGINEERING CONTROLS
No special requirements. Product is used outdoors.
PERSONAL PROTECTION
Avoid contact with eyes and skin. Do not inhale spray mist. When preparing the spray wear cotton overalls
buttoned to the neck and wrist, washable hat, elbow-length PVC gloves, impervious footwear and a face-shield
or goggles. If clothing becomes contaminated with product remove clothing immediately. If product gets on
skin immediately wash area with soap and water. After use and before eating, drinking or smoking, wash
hands, arms and face thoroughly with soap and water. Wear a half face-piece respirator with combined dust
and vapour cartridge if the level of the aromatic hydrocarbon solvent is likely to exceed the recommended
exposure standard given above.
FLAMMABILITY
This product is NON-FLAMMABLE. Product is combustible.
TOPAS 200 EW
SAFE HANDLING INFORMATION
STORAGE AND TRANSPORT
Store in the tightly sealed, original containers in a dry, secure, well-ventilated place away from fertilisers, seed,
feed and food. Store out of direct sunlight. Keep out of reach of children, unauthorised persons and animals.
Avoid temperatures below -5?? and above 35??
C C
SPILLS AND DISPOSAL
In case of spillage it is important to take all steps necessary to:
?? Avoid eye and skin contact.
?? Avoid contamination of waterways.
Procedure for spill:
(1) Keep all bystanders away.
(2) Wear goggles, half face-piece respirator with combined dust and vapour cartridge, full length clothing and
PVC gloves.
(3) Reposition any leaking containers so as to minimise further leakage.
(4) Dam and absorb spill with an absorbent material (e.g. sand or soil).
(5) Shovel the absorbed spill into drums.
(6) Disposal of the absorbed material will depend upon the extent of the spill.
?? For quantities up to 50 L of product bury in a secure landfill site.
?? For quantities greater than 50 L seek advice from the manufacturer (use emergency contact number
below) before attempting disposal. Contain in a secure location until disposal method is established.
(7) Decontaminate the spill area with detergent and water and rinse with the smallest volume of water
practicable
Dispose of empty, used containers by:
(a) Triple rinsing or preferably pressure rinsing containers with water. Add the rinsings to the spray tank. DO
NOT dispose of undiluted chemicals on site.
(b) If recycling, replace cap and return clean containers to recycle to designated collection point.
(c) If not recycling, break, crush or puncture and bury empty containers in a local authority landfill. If no
landfill is available, bury the containers below 500 mm in a disposal pit specifically marked and set up for
this purpose clear of waterways, desirable vegetation and tree roots.
(d) Burning of empty containers if circumstances, especially wind direction, permit is an alternative method.
FIRE/EXPLOSION HAZAR This product is non-flammable and non-explosive. Product is combustible. Extinguish warehouse and factory
fires using fine-water spray powder, carbon dioxide or foam. During a fire this product may release smoke and
hazardous decomposition products which are toxic or irritant. When fighting a major fire wear an air-supplied
respirator.
OTHER INFORMATION
Penconazole technical is practically non-toxic to birds and bees and moderately toxic to fish
[LC50 (96 h), rainbow trout = 1.7 - 4.3 mg/L].
Product is harmful to fish and daphniae. Toxic to algae.
Note: This product is a registered agricultural chemical and must therefore be used in accordance with the container label directions.
A comprehensive package of toxicological and environmental data for the active ingredients of this product has been
submitted to the Government health and environment authorities and has been evaluated by expert toxicologists and
environmental scientists.
CONTACT POINT: Business Manager - Crop Protection (09) 306 1500
24 HOURS EMERGENCY CONTACT: 0800 734 607
This Material Safety Data Sheet summarises our best knowledge of the health and safety hazard information of the product and how to
safely handle and use the product in the workplace. Each user should read this MSDS and consider the information in the context of
how the product will be handled and used in the workplace including in conjunction with other products.
If clarification or further information is needed to ensure that an appropriate risk assessment can be made, the user should contact this
company.
? Registered Trade Mark of a Syngenta Group Company.
Fatty acids, C6-10 methyl esters
China (Mainland)] 
Assessed