*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : RP6500000
CHEMICAL NAME : 4H-(1,3)Oxazino(3,2-d)(1,4)benzodiazepine-4,7(6H)-dio
ne, 8,12b-dihydro-11-chloro-2,8- dimethyl-12b-phenyl-
CAS REGISTRY NUMBER : 27223-35-4
LAST UPDATED : 198702
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C20-H17-Cl-N2-O3
MOLECULAR WEIGHT : 368.84
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Anxon
* Ketazolam
* U-28,774
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MDACAP Medicamentos de Actualidad. (J.R. Prous, S.A., Apartado de Correos
540, 08080 Barcelona, Spain) V.1- 1965- Volume(issue)/page/year:
16,293,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MDACAP Medicamentos de Actualidad. (J.R. Prous, S.A., Apartado de Correos
540, 08080 Barcelona, Spain) V.1- 1965- Volume(issue)/page/year:
16,293,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Mammal - cat
DOSE/DURATION : 3900 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MDACAP Medicamentos de Actualidad. (J.R. Prous, S.A., Apartado de Correos
540, 08080 Barcelona, Spain) V.1- 1965- Volume(issue)/page/year:
16,293,1980
*** END OF RECORD ***
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ketazolam