Oleandomycin,2'',4',11-triacetate MSDS CasNo.2751-09-9

Position: Index > Categories > Semiconductors and Actives

CAS : 2751-09-9

MSDS	:	Oleandomycin, triacetate (ester)
CAS	:	2751-09-9
SYNONYMS	:	* Cyclamycin * Evramicina * Oleandomycin triacetate * Oleandomycin triacetyl ester * TAO * Triacetyloleandomycin * Troleandomycin * WY 651

Catalog of Chemical Suppliers, Buyers, Custom Synthesis Companies And Equipment Manufacturers
[ Oleandomycin, triacetate (ester) 2751-09-9 ]

                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RJ9900000
CHEMICAL NAME           : Oleandomycin, triacetate (ester)
CAS REGISTRY NUMBER     : 2751-09-9
LAST UPDATED            : 199312
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C41-H67-N-O15
MOLECULAR WEIGHT        : 814.09
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Cyclamycin
   * Evramicina
   * Oleandomycin triacetate
   * Oleandomycin triacetyl ester
   * TAO
   * Triacetyloleandomycin
   * Troleandomycin
   * WY 651
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
   Skin and Appendages - hair
REFERENCE :
   ANTCAO Antibiotics and Chemotherapy (Washington, DC).  (Washington, DC)
   V.1-12, 1951-62.  For publisher information, see CLMEA3.
   Volume(issue)/page/year: 8,528,1958
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 117 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - tremor
   Behavioral - ataxia
REFERENCE :
   ANTCAO Antibiotics and Chemotherapy (Washington, DC).  (Washington, DC)
   V.1-12, 1951-62.  For publisher information, see CLMEA3.
   Volume(issue)/page/year: 8,528,1958
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,515,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 198 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,514,1982
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 13650 mg/kg/13W-C
TOXIC EFFECTS :
   Endocrine - changes in adrenal weight
   Blood - other changes
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   119,181,1993
 
                            *** END OF RECORD ***

TROLEANDOMYCIN