3-Isoxazolecarboxylic acid, 5-methyl-,
2-(p-(dimethylamino)benzyl)hydrazide

CAS  

 328-33-6

SYNONYMS  

 * 3-Isoxazolecarboxylic acid, 5-methyl-,
2-((4-(dimethylamino)phenyl)methyl)hydrazide
* 5-Methyl-3-isoxazolecarboxylic acid 2-(p-(dimethylamino)benzyl)hydrazide
* Ro 5-1025

                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NY2715000
CHEMICAL NAME           : 3-Isoxazolecarboxylic acid, 5-methyl-,
                          2-(p-(dimethylamino)benzyl)hydrazide
CAS REGISTRY NUMBER     : 328-33-6
BEILSTEIN REFERENCE NO. : 0888583
LAST UPDATED            : 199709
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C14-H18-N4-O2
MOLECULAR WEIGHT        : 274.36
WISWESSER LINE NOTATION : T5NOJ C1 EVMM1R DN1&1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3-Isoxazolecarboxylic acid, 5-methyl-,  
   2-((4-(dimethylamino)phenyl)methyl)hydrazide
   * 5-Methyl-3-isoxazolecarboxylic acid 2-(p-(dimethylamino)benzyl)hydrazide
   * Ro 5-1025
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 210 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMPCAS Journal of Medicinal and Pharmaceutical Chemistry.  (Washington, DC)
   V.1-5, 1959-62.  For publisher information, see JMCMAR.
   Volume(issue)/page/year: 3,241,1961
 
                            *** END OF RECORD ***