|
1.
1.1
IDENTIFICATION
OF
THE
SUBSTANCE/MIXTURE
AND
OF
THE
COMPANY/UNDERTAKING
Product
identifiers
Product
name
Product
Number
Brand
Index-No.
CAS-No.
:
:
:
:
:
Dichloromethane
02575
Fluka
602-004-00-3
75-09-2
1.2
Relevant
identified
uses
of
the
substance
or
mixture
and
uses
advised
against
Identified
uses
:
Laboratory
chemicals,
Manufacture
of
substances 2.
2.1
2.2
HAZARDS
IDENTIFICATION
Classification
of
the
substance
or
mixture
Classification
according
to
Regulation
(EC)
No
1272/2008
[EU-GHS/CLP]
Carcinogenicity
(Category
2)
Classification
according
to
EU
Directives
67/548/EEC
or
1999/45/EC
Limited
evidence
of
a
carcinogenic
effect.
Label
elements
Labelling
according
Regulation
(EC)
No
1272/2008
[CLP]
Pictogram
Signal
word
Hazard
statement(s)
H351
Precautionary
statement(s)
P281
Supplemental
Hazard
Warning
Suspected
of
causing
cancer.
Use
personal
protective
equipment
as
required.
none
Statements
According
to
European
Directive
67/548/EEC
as
amended.
Hazard
symbol(s)
R-phrase(s)
R40
S-phrase(s)
S23
S24/25
S36/37
Limited
evidence
of
a
carcinogenic
effect.
Do
not
breathe
gas/fumes/vapour/spray.
Avoid
contact
with
skin
and
eyes.
Wear
suitable
protective
clothing
and
gloves.
2.3
3.
3.1
Other
hazards
-
none
COMPOSITION/INFORMATION
ON
INGREDIENTS
Substances
Synonyms
Formula
Molecular
Weight
Component
Methylene
chloride
:
:
:
Methylene
chloride
CH2Cl2
84,93
g/mol
Concentration
CAS-No.
EC-No.
Index-No.
75-09-2
200-838-9
602-004-00-3
-
4.
4.1
4.2
4.3
5.
5.1
FIRST
AID
MEASURES
Description
of
first
aid
measures
General
advice
Consult
a
physician.
Show
this
safety
data
sheet
to
the
doctor
in
attendance.
If
inhaled
If
breathed
in,
move
person
into
fresh
air.
If
not
breathing,
give
artificial
respiration.
Consult
a
physician.
In
case
of
skin
contact
Wash
off
with
soap
and
plenty
of
water.
Consult
a
physician.
In
case
of
eye
contact
Rinse
thoroughly
with
plenty
of
water
for
at
least
15
minutes
and
consult
a
physician.
If
swallowed
Never
give
anything
by
mouth
to
an
unconscious
person.
Rinse
mouth
with
water.
Consult
a
physician.
Most
important
symptoms
and
effects,
both
acute
and
delayed
Dichloromethane
is
metabolized
in
the
body
producing
carbon
monoxide
which
increases
and
sustains
carboxyhemoglobin
levels
in
the
blood,
reducing
the
oxygen-carrying
capacity
of
the
blood.,
Acts
as
a
simple
asphyxiant
by
displacing
air.,
anesthetic
effects,
Difficulty
in
breathing,
Headache,
Dizziness,
Prolonged
or
repeated
contact
with
skin
may
cause:,
defatting,
Dermatitis,
Contact
with
eyes
can
cause:,
Redness,
Blurred
vision,
Provokes
tears.,
Effects
due
to
ingestion
may
include:,
Gastrointestinal
discomfort,
Central
nervous
system
depression,
Paresthesia.,
Drowsiness,
Convulsions,
Conjunctivitis.,
Pulmonary
edema.
Effects
may
be
delayed.,
Irregular
breathing.,
Stomach/intestinal
disorders,
Nausea,
Vomiting,
Increased
liver
enzymes.,
Weakness,
Heavy
or
prolonged
skin
exposure
may
result
in
the
absorption
of
harmful
amounts
of
material.,
Abdominal
pain
Indication
of
any
immediate
medical
attention
and
special
treatment
needed
no
data
available
FIREFIGHTING
MEASURES
Extinguishing
media
Suitable
extinguishing
media
Use
water
spray,
alcohol-resistant
foam,
dry
chemical
or
carbon
dioxide.
5.2
5.3
5.4
6.
6.1
6.2
6.3
6.4
7.
7.1
7.2
7.3
8.
8.1
8.2
Special
hazards
arising
from
the
substance
or
mixture
Carbon
oxides,
Hydrogen
chloride
gas
Advice
for
firefighters
Wear
self
contained
breathing
apparatus
for
fire
fighting
if
necessary.
Further
information
no
data
available
ACCIDENTAL
RELEASE
MEASURES
Personal
precautions,
protective
equipment
and
emergency
procedures
Use
personal
protective
equipment.
Avoid
breathing
vapors,
mist
or
gas.
Ensure
adequate
ventilation.
Evacuate
personnel
to
safe
areas.
Environmental
precautions
Prevent
further
leakage
or
spillage
if
safe
to
do
so.
Do
not
let
product
enter
drains.
Methods
and
materials
for
containment
and
cleaning
up
Soak
up
with
inert
absorbent
material
and
dispose
of
as
hazardous
waste.
Keep
in
suitable,
closed
containers
for
disposal.
Reference
to
other
sections
For
disposal
see
section
13.
HANDLING
AND
STORAGE
Precautions
for
safe
handling
Avoid
contact
with
skin
and
eyes.
Avoid
inhalation
of
vapour
or
mist.
Conditions
for
safe
storage,
including
any
incompatibilities
Store
in
cool
place.
Keep
container
tightly
closed
in
a
dry
and
well-ventilated
place.
Containers
which
are
opened
must
be
carefully
resealed
and
kept
upright
to
prevent
leakage.
Heat
sensitive.
Store
under
inert
gas.
Specific
end
uses
no
data
available
EXPOSURE
CONTROLS/PERSONAL
PROTECTION
Control
parameters
Components
with
workplace
control
parameters
Exposure
controls
Appropriate
engineering
controls
Handle
in
accordance
with
good
industrial
hygiene
and
safety
practice.
Wash
hands
before
breaks
and
at
the
end
of
workday.
Personal
protective
equipment
Eye/face
protection
Face
shield
and
safety
glasses
Use
equipment
for
eye
protection
tested
and
approved
under
appropriate
government
standards
such
as
NIOSH
(US)
or
EN
166(EU).
Skin
protection
Handle
with
gloves.
Gloves
must
be
inspected
prior
to
use.
Use
proper
glove
removal
technique
(without
touching
glove's
outer
surface)
to
avoid
skin
contact
with
this
product.
Dispose
of
contaminated
gloves
after
use
in
accordance
with
applicable
laws
and
good
laboratory
practices.
Wash
and
dry
hands.
The
selected
protective
gloves
have
to
satisfy
the
specifications
of
EU
Directive
89/686/EEC
and
the
standard
EN
374
derived
from
it.
Body
Protection
Complete
suit
protecting
against
chemicals,
The
type
of
protective
equipment
must
be
selected
according
to
the
concentration
and
amount
of
the
dangerous
substance
at
the
specific
workplace.
Respiratory
protection
Where
risk
assessment
shows
air-purifying
respirators
are
appropriate
use
a
full-face
respirator
with
multi-purpose
combination
(US)
or
type
AXBEK
(EN
14387)
respirator
cartridges
as
a
backup
to
engineering
controls.
If
the
respirator
is
the
sole
means
of
protection,
use
a
full-face
supplied
air
respirator.
Use
respirators
and
components
tested
and
approved
under
appropriate
government
standards
such
as
NIOSH
(US)
or
CEN
(EU).
9.
9.1
PHYSICAL
AND
CHEMICAL
PROPERTIES
Information
on
basic
physical
and
chemical
properties
a)
b)
c)
d)
e)
f)
g)
h)
Appearance
Odour
Odour
Threshold
pH
Melting
point/freezing
point
Initial
boiling
point
and
boiling
range
Flash
point
Evaporation
rate
Form:
liquid
Colour:
colourless
no
data
available
no
data
available
no
data
available
Melting
point/range:
-97
°C
39,8
-
40
°C
no
data
available
0,71
i)
Flammability
(solid,
gas)
no
data
available
j)
k)
l)
Upper/lower
flammability
or
explosive
limits
Vapour
pressure
Vapour
density
Upper
explosion
limit:
19
%(V)
Lower
explosion
limit:
12
%(V)
470,9
hPa
at
20,0
°C
2,93
-
(Air
=
1.0)
m)
Relative
density
1,325
g/mL
at
25
°C
n)
o)
p)
q)
r)
s)
t)
Water
solubility
Partition
coefficient:
n-
octanol/water
Autoignition
temperature
Decomposition
temperature
Viscosity
Explosive
properties
Oxidizing
properties
slightly
soluble
log
Pow:
1,25
556,1
°C662,0
°C
no
data
available
no
data
available
no
data
available
no
data
available
9.2
10.
10.1
10.2
10.3
Other
safety
information
no
data
available
STABILITY
AND
REACTIVITY
Reactivity
no
data
available
Chemical
stability
no
data
available
Contains
the
following
stabiliser(s):
2-Methyl-2-butene
(0,002
%)
Possibility
of
hazardous
reactions
no
data
available
10.4
10.5
10.6
11.
11.1
Conditions
to
avoid
Heat,
flames
and
sparks.
Exposure
to
sunlight.
Incompatible
materials
Alkali
metals,
Aluminum,
Strong
oxidizing
agents,
Bases,
Amines,
Magnesium,
Strong
acids
and
strong
bases,
Vinyl
compounds
Hazardous
decomposition
products
Other
decomposition
products
-
no
data
available
TOXICOLOGICAL
INFORMATION
Information
on
toxicological
effects
Acute
toxicity
LD50
Oral
-
rat
-
1.600
mg/kg
Remarks:
Behavioral:Ataxia.
LC50
Inhalation
-
rat
-
52.000
mg/m3
Skin
corrosion/irritation
Skin
-
rabbit
-
Skin
irritation
-
24
h
Serious
eye
damage/eye
irritation
Eyes
-
rabbit
-
Mild
eye
irritation
-
24
h
Respiratory
or
skin
sensitization
no
data
available
Germ
cell
mutagenicity
Genotoxicity
in
vivo
-
rat
-
Oral
DNA
damage
Carcinogenicity
Carcinogenicity
-
rat
-
Inhalation
Tumorigenic:Carcinogenic
by
RTECS
criteria.
Endocrine:Tumors.
Limited
evidence
of
carcinogenicity
in
animal
studies
IARC:
2B
-
Group
2B:
Possibly
carcinogenic
to
humans
(Methylene
chloride)
Reproductive
toxicity
no
data
available
Specific
target
organ
toxicity
-
single
exposure
no
data
available
Specific
target
organ
toxicity
-
repeated
exposure
no
data
available
Aspiration
hazard
no
data
available
Potential
health
effects
Inhalation
Ingestion
Skin
Eyes
May
be
harmful
if
inhaled.
Causes
respiratory
tract
irritation.
Harmful
if
swallowed.
May
be
harmful
if
absorbed
through
skin.
Causes
skin
irritation.
Causes
eye
irritation.
Signs
and
Symptoms
of
Exposure
Dichloromethane
is
metabolized
in
the
body
producing
carbon
monoxide
which
increases
and
sustains
carboxyhemoglobin
levels
in
the
blood,
reducing
the
oxygen-carrying
capacity
of
the
blood.,
Acts
as
a
simple
asphyxiant
by
displacing
air.,
anesthetic
effects,
Difficulty
in
breathing,
Headache,
Dizziness,
Prolonged
or
repeated
contact
with
skin
may
cause:,
defatting,
Dermatitis,
Contact
with
eyes
can
cause:,
Redness,
Blurred
vision,
Provokes
tears.,
Effects
due
to
ingestion
may
include:,
Gastrointestinal
discomfort,
Central
nervous
system
depression,
Paresthesia.,
Drowsiness,
Convulsions,
Conjunctivitis.,
Pulmonary
edema.
Effects
may
be
delayed.,
Irregular
breathing.,
Stomach/intestinal
disorders,
Nausea,
Vomiting,
Increased
liver
enzymes.,
Weakness,
Heavy
or
prolonged
skin
exposure
may
result
in
the
absorption
of
harmful
amounts
of
material.,
Abdominal
pain
Additional
Information
RTECS:
PA8050000
12.
12.1
ECOLOGICAL
INFORMATION
Toxicity
Toxicity
to
fish
Toxicity
to
daphnia
and
other
aquatic
invertebrates
LC50
-
Pimephales
promelas
(fathead
minnow)
-
193,00
mg/l
-
96
h
NOEC
-
Cyprinodon
variegatus
(sheepshead
minnow)
-
130
mg/l
-
96
h
EC50
-
Daphnia
magna
(Water
flea)
-
1.682,00
mg/l
-
48
h
12.2
12.3
12.4
12.5
12.6
13.
13.1
14.
14.1
Persistence
and
degradability
no
data
available
Bioaccumulative
potential
no
data
available
Mobility
in
soil
no
data
available
Results
of
PBT
and
vPvB
assessment
no
data
available
Other
adverse
effects
no
data
available
DISPOSAL
CONSIDERATIONS
Waste
treatment
methods
Product
Offer
surplus
and
non-recyclable
solutions
to
a
licensed
disposal
company.
Contaminated
packaging
Dispose
of
as
unused
product.
TRANSPORT
INFORMATION
UN
number
14.2
14.3
14.4
14.5
14.6
15.
ADR/RID:
1593
UN
proper
shipping
name
ADR/RID:
DICHLOROMETHANE
IMDG:
DICHLOROMETHANE
IATA:
Dichloromethane
Transport
hazard
class(es)
ADR/RID:
6.1
Packaging
group
ADR/RID:
III
Environmental
hazards
ADR/RID:
yes
Special
precautions
for
user
no
data
available
REGULATORY
INFORMATION
IMDG:
1593
IMDG:
6.1
IMDG:
III
IMDG
Marine
pollutant:
yes
IATA:
1593
IATA:
6.1
IATA:
III
IATA:
no
This
safety
datasheet
complies
with
the
requirements
of
Regulation
(EC)
No.
1907/2006.
15.1
Safety,
health
and
environmental
regulations/legislation
specific
for
the
substance
or
mixture
no
data
available
15.2
16.
Chemical
Safety
Assessment
no
data
available
OTHER
INFORMATION
Further
information
The above information is believed to be correct but does not purport to be all inclusive and
shall be used only as a guide. The information this document is based on the resent state
of our knowledge and is applicable to the product with regard to appropriate safety precautions.
It does not represent any guarantee of the properties of the product. Lookchem shall not be
held liable for any damage resulting from handling or from contact with the above product.
See reverse side of invoice or packing slip for additional terms and conditions of sale.
| 
Dichloromethane