USD $1.00-1.00 / Kilogram
USD $100.00-150.00 / Kilogram
USD $1.00-10.00 / Kilogram
USD $1.00-10.00 / Kilogram
USD $1.00-10.00 / Kilogram
USD $2.00-10.00 / Kilogram
USD $2.00-10.00 / Kilogram
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plerixafor basic information |
product name: | plerixafor |
synonyms: | plerixafor;1,1'-[1,4-phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane;1,4,8,11-tetraazacyclotetradecane, 1,1'-(1,4-phenylenebis(methylene))bis-;mozobil;sdz sid 791;unii-s915p5499n;1-[[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methyl]-1,4,8,11-tetrazacyclotetradecane;plerixafor(amd3100) |
cas: | 110078-46-1 |
mf: | c28h54n8 |
mw: | 502.791 |
einecs: | |
product categories: | aromatics;heterocycles;inhibitors;intermediates & fine chemicals;pharmaceuticals |
mol file: | 110078-46-1.mol |
plerixafor chemical properties |
mp | 122-125°c |
density | 0.962 |
storage temp. | refrigerator |
safety information |
plerixafor usage and synthesis |
chemical properties | white solid |
usage | plerixafor is a chemokine receptor antagonist for cxcr4 and cxcl12-mediated chemotaxis with ic50 of 44 nm and 5.7 nm, respectively |
usage | plerixafor is a hematopoietic stem cell (hsc) mobilizer that inhibits the cxcr4 chemokine receptor and blocks binding of its ligand, stromal cell-derived factor-1-α (sdf-1-α). on dec. 15, 2008, as treatment in combination with granulocyte-colony stimulating factor (g-csf) to mobilize hscs to the peripheral blood for collection and subsequent autologous transplantation in p atients with non-hodgkin's lymphoma (nhl) and multiple myeloma (mm). |