26116-56-3 (9S)-9-Amino-9-deoxoerythromycin CAS NO.26116-56-3

(9s)-9-amino-9-deoxoerythromycin chemical properties

melting point 123-127°c

storage temp. -20°c freezer

safety information

hazard codes xi,n

risk statements 41-50/53

safety statements 26-39-60-61

msds information

(9s)-9-amino-9-deoxoerythromycin usage and synthesis

chemical properties white solid

uses erythromycylamine is a semi-synthetic analogue of erythromycin prepared by reduction of erythromycin oxime. erythromycyclamine is a potent antibiotic, however the introduction of the amino- moiety increases the compound’s polarity and is disadvantageous for in vivo use. this limitation was overcome by the synthesis of dirithromycin, a schiff base pro-drug that dissociates in vivo to erythromycylamine.

uses erythromycylamine is a semi-synthetic analogue of erythromycin prepared by reduction of erythromycin oxime. erythromycylamine is a potent antibiotic, however the introduction of the amino- moiety increases the compound’s polarity and is disadvantageous for in vivo use. this limitation was overcome by the synthesis of dirithromycin, a schiff base pro-drug that dissociates in vivo to erythromycylamine.

uses a metabolite of dirithromycin; an antibiotic

definition chebi: a macrolide antibiotic that is erythromycin a in which the ketone group has been converted to the corresponding imine and then reduced to give the corresponding amino compound (the 9s diastereoisomer).