99%min Liranaftate 88678-31-3 CAS NO.88678-31-3

Min.Order Quantity:: 10 Gram

Purity:: 99%

Port:: Wuhan

Payment Terms:: T/T,MoneyGram

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Product Details

Keywords

99%min Liranaftate
Liranaftate Manufacturer
For Antifungal

Quick Details

ProName: 99%min Liranaftate 88678-31-3
CasNo: 88678-31-3
Molecular Formula: C18H20N2O2S
Appearance: White Powder
Application: It Can Be Used As Pharmaceutical Inte...
DeliveryTime: 2-4 days after confirming your payment...
PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
Port: Wuhan
ProductionCapacity: 10000 Metric Ton/Month
Purity: 99%
Storage: Store in sealed containers at cool & d...
Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
LimitNum: 10 Gram

Superiority

advantages:

hubei xinrunde chemical co., ltd is a renowned pharmaceutical manufacturer. we can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. never stop striving to offer our best service is our philosophy. we have flexible and untraceable payment terms. as a leading manufacture, our products have been exported to germany, norway, poland, finland, spain, uk, france, russia, usa, brazil, mexico, australia, japan, korea, thailand, indonesia, uruguay and many other countries.

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4. warm after-sale service any of your question would be solved for the first as soon as possible.

Details

liranaftate basic information

the third generation of dithiocarbamate antifungal toxicity synthesis method liranaftate cream uses

product name:	liranaftate
synonyms:	carbamothioicacid,(6-methoxy-2-pyridinyl)methyl-,o-(5,6,7,8-tetrahydro-2-na;phthalenyl)ester;liranafate;liranaftate;m-732;(6-methoxy-2-pyridinyl)-methylcarbamothioic acid o-(5,6,7,8-tetrahydro-2-naphthalenyl) ester;piritetrate;zefnart
cas:	88678-31-3
mf:	c18h20n2o2s
mw:	328.43
einecs:	-0
product categories:	all inhibitors;inhibitors;intermediates & fine chemicals;pharmaceuticals;liranaftate;api
mol file:	88678-31-3.mol

liranaftate chemical properties

melting point	98.5-99.5°c
storage temp.	-20°c freezer
merck	14,5515

safety information

rtecs

fd3890000

liranaftate usage and synthesis

the third generation of dithiocarbamate antifungal

liranaftate is a new king of third-generation dithiocarbamate antifungals , it is a new kind of the third category of chemicals,it belongs to squalene cyclooxygenase inhibitors, by inhibiting the fungal cell membrane squalene epoxidation reaction , it hinders the synthesis of ergosterol which is a constituent of cell membranes ,it plays the role of anti-fungal,its anti-fungal activity is 8 times of tolnaftate, and its dermatophytes effect is better than clotrimazole. it has a strong anti-fungal effect on skin filamentous fungi (trichophyton,microsporon, epidermophyton) , it also shows antifungal activity on other filamentous fungi, dark fungi, dimorphic fungi.it is useful in the treatment of tinea capitis, ringworm, athlete's foot, tinea pedis, onychomycosis, tinea, jock itch, tinea versicolor and vulvovaginal candidiasis.

toxicity

reproductive toxicity: in general reproductive toxicity tests, subcutaneous administration to sd rats , the largest non-toxic dose for the parent is 20mg/kg, the largest non-toxic dose for the reproductive process and their pups is 100mg/kg.
genetic toxicity: liranaftate mutagenicity tests are negative.
in toxicity tests during teratogenic sensitively period , subcutaneous administration ,the largest non-toxic dose of maternal is 300mg/kg, the largest non-toxic dose to fetal rats is100mg/kg.
in perinatal toxicity tests, administer subcutaneously, the largest non-toxic dose for the mother and newborn pups is 30mg/kg.
the above information is edited by the chemicalbook of tian ye.

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