Aprepitant Manufacturer For Chemotherapy Vomiting Medicine CAS NO.170729-80-3

Min.Order Quantity:: 10 Gram

Purity:: 99%min

Port:: ShangHai

Payment Terms:: T/T,MoneyGram

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Product Details

Keywords

99%min Aprepitant
Aprepitant Manufacturer
For Chemotherapy Vomiting Medicine

Quick Details

ProName: Aprepitant Manufacturer For Chemother...
CasNo: 170729-80-3
Molecular Formula: C23H21F7N4O3
Appearance: White Powder
Application: For Pharmaceutical Raw Materials
DeliveryTime: 2-4 days after confirmed your payments
PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
Port: ShangHai
ProductionCapacity: 1000 Metric Ton/Month
Purity: 99%min
Storage: Dry and cool place
Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
LimitNum: 10 Gram

Superiority

advantages:

hubei xinrunde chemical co., ltd is a renowned pharmaceutical manufacturer. we can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. never stop striving to offer our best service is our philosophy. we have flexible and untraceable payment terms. as a leading manufacture, our products have been exported to germany, norway, poland, finland, spain, uk, france, russia, usa, brazil, mexico, australia, japan, korea, thailand, indonesia, uruguay and many other countries.

1. quality.every batch of steroid powders have tobetested by our qc(quality control) before they are allowed to sell.

2 . delivery we have stock, so we can delivery quickly at the very day when receive the payment. within 24 hours after receiving the payment lead time 4 or 7 days.

3 . discreet package safelyand professionally disguised package guaranteed. for your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate

4 . warm after-sale service any of your question would be solved for the first as soon as possible.

Details

aprepitant basic information

anti-vomiting drug during chemotherapy dose and usage side effects uses

product name:	aprepitant
synonyms:	aprepitant;5-[[(2r,3s)-2-[(1r)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3h-1,;5-[[(2r,3s)-2-[(1r)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3h-1,2,4-triazol-3-one, emend;5-[[(2r,3s)-2-[(1r)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3h-1,2,4-triazol-3-one;emend;mk-0869;aprepitant(mk-0869);ono 7436
cas:	170729-80-3
mf:	c23h21f7n4o3
mw:	534.4266624
einecs:	1806241-263-5
product categories:	chiral reagents;heterocycles;intermediates & fine chemicals;pharmaceuticals;pharmaceutical intermediate;aprepitant;inhibitors
mol file:	170729-80-3.mol

aprepitant chemical properties

melting point	244-246°c
alpha	d25 +69° (c = 1.00 in methanol)
storage temp.	-20°c freezer
cas database reference	170729-80-3(cas database reference)

description	aprepitant is an antiemetic chemical compound that belongs to “substance p” antagonists (spa) with its effect being blocking the neurokinin 1(nk1) receptor. it is used for the prevention of acute and delayedchemotherapy-induced nausea and vomiting(cinv) and for prevention ofpostoperative nausea and vomiting. it can also be used for the treatment of cyclic vomiting syndrome and late-stage chemotherapy induced vomiting occurring during cancer treatment. aprepitant alleviates the case of vomiting in patients through balking the signals released by nk1 receptors. nk1 is a g-protein-coupled receptor with its ligand being substance p (sp). the high concentration of sp is required for the vomiting reflex. aprepitant blocks the process of sp-nk1 signaling in activating the vomiting reflex.
chemical properties	off-white to light yellow cyrstalline solid
uses	a novel selective neurokinin-1 (nk-1) receptor antagonist. in vitro studies using human liver microsomes indicate that aprepitant is metabolised primarily by cyp3a4 with minor metabolism by cyp1a2 and cyp2c19, and no metabolism by cyp2d6, cyp2c9, or cyp2e1. antiemetic.
uses	anticholinergic