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HENAN SUNLAKE ENTERPRISE CORPORATIONAstemizole//file1.lookchem.com/300w/synthetic/2022-01-29-04/890350ba-489e-4244-87a6-8c86c939c278.png
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Astemizole CAS NO.68844-77-9

Min.Order Quantity:
1 Kilogram
Purity:
99%
Port:
China Main Port
Payment Terms:
L/C,D/A,D/P,T/T,MoneyGram,Other

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Product Details

Keywords

  • Astemizole
  • 68844-77-9
  • C28H31FN4O

Quick Details

  • ProName: Astemizole
  • CasNo: 68844-77-9
  • Molecular Formula: C28H31FN4O
  • Appearance: Crystalline Solid
  • Application: 68844-77-9
  • DeliveryTime: Within 3-7days
  • PackAge: As requested
  • Port: China Main Port
  • ProductionCapacity: 300 Kilogram/Day
  • Purity: 99%
  • Storage: Store at +4°C
  • Transportation: By air or by sea
  • LimitNum: 1 Kilogram

Superiority

astemizole basic information
product name: astemizole
synonyms: 1-((4-fluorophenyl)methyl)-n-(1-(2-(4-methoxyphenyl)ethyl)-4-piperidinyl)-1h-b;1-(p-fluorobenzyl)-2-((1-(2-(p-methoxyphenyl)ethyl)piperid-4-yl)amino)benzim;1-(p-fluorobenzyl)-2-((1-(p-methoxyphenethyl)-4-piperidyl)amino)benzimidazole;1h-benzimidazol-2-amine,1-((4-fluorophenyl)methyl)-n-(1-(2-(4-methoxyphenyl)et;astemison;astemizol;astemizol(inn-spanish);astemizolum(inn-latin)
cas: 68844-77-9
mf: c28h31fn4o
mw: 458.57
einecs: 272-441-9
product categories: aromatics;heterocycles;intermediates & fine chemicals;pharmaceuticals;histamine receptor;amines;ascabiol
mol file: 68844-77-9.mol
astemizole structure
astemizole chemical properties
melting point 172.9°c
storage temp. store at +4°c
safety information
hazard codes xn
risk statements 22-36/37/38
safety statements 26-36
wgk germany 3
rtecs dd8968000
hazardous substances data 68844-77-9(hazardous substances data)
astemizole usage and synthesis
chemical properties crystalline solid
usage nonsedating-type histamine h1-receptor antagonist. potential for combination therapy with antivancer drugs such as doxorubicin in resistant leukemia. antihistaminic
usage scabicide
biological activity orally active, potent histamine h 1 antagonist (ic 50 = 4 nm) that displays 20-fold, > 250-fold and > 250-fold selectivity over 5-ht, dopamine and muscarinic acetylcholine receptors respectively. exhibits antimalarial activity in multidrug resistant strains in vitro (ic 50 = 227 - 734 nm). also potent herg k + channel blocker (ic 50 = 0.9 nm) that displays cardiotoxicity in vivo .
astemizole preparation products and raw materials
raw materials iodomethane-->bromoethane-->1,4-dimethoxybenzene

Details

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