USD $10.00-10.00 / Gram
USD $10.00-10.00 / Gram
USD $10.00-10.00 / Gram
USD $10.00-10.00 / Gram
flunixin meglumin
flunixin meglumine ;flunixin meglumine is a potent, non-narcotic, non-steroidal analgesic agent with anti-inflammatory and antipyretic activity. it is a potent inhibitor of the enzyme cyclooxygenase. it has demonstrated biological activity in the following areas:
testing items |
specifications |
results |
appearance |
white to almost white, crystalline powder |
conforms |
solubility |
freely soluble in water and methanol, paractically insoluble in acetone |
conforms |
identification 1 |
infrared absorption:197m;u ltraviolet absorption:197u |
conforms |
identification 2 |
water: free soluble;ethanol(96%):free soluble ethyl acetate: practically insoluble |
conforms |
melting point |
137~140℃ |
137.5~138.5 |
ph |
5 %(w/v)water solution:7.0~9.0 |
8.2 |
related substances |
2-chloropyridine-3carboxylic acid ≤0.2% |
undetected |
2-methyl-3-(trifluoromethyl)aniline ≤0.2% |
undetected |
|
ethyl 2-chloropyridine-3-carboxylate ≤0.2% |
undetected |
|
ethyl 2-[[2-methyl-3-(trifluoromethyl) phenyl]amino]pyridine-3-carboxylate ≤0.2% |
undetected |
|
impurities |
1. single impurity: not more than 0.2% |
conforms |
2. unknown impurity: not more than 0.2% |
conforms |
|
total impurities(1~2): not more than 0.5% |
conforms |
|
specific optical rotation |
-9.0°~ -12.0° |
-10.3° |
solvent residue |
isopropanol: not more than 0.5% |
conforms |
|
ethanol: not more than 0.5% |
conforms |
bacterial endotoxins |
not more than 4.54 eu/mg |
0.1 eu/mg |
loss on drying |
≤0.5% |
0.2% |
sulphated ash |
≤0.1% |
0.05% |
residue on ignition |
≤0.2% |
0.1% |
colour of solution |
clear,less coloured than reference solution y6,b.p.(vet) |
conforms |
clarification |
1.2g funixin meglumine/8.8g water |
transparent |
explanation |
micronisarion 200±20um |
|
assay (hplc) |
99.0~101.0% |
99.64% |
conclusion |
comply with usp 37/ep7/bpv2012 |
|
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