Pemetrexed disodium CAS NO.150399-23-8

product name:

pemetrexed disodium

synonyms:

n-[4-[2-(2-amino-4,7-dihydro-4-oxo-1h-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-l-glutamic acid disodium salt;pemetrexed disodium;pemetrexed disodium(alimta);pemetrexed sodium;pemetrexed;2-[4-[2-(4-amino-2-oxo-3,5,7-triazabicyclo[4.3.0]nona-3,8,10-trien-9-yl)ethyl]benzoyl]aminopentanedioic acid disodium salt;pemetrexed disodium 99%;pemetrexed disodium 2.5h2o

cas:

150399-23-8

mf:

c20h19n5na2o6

mw:

471.37

product categories:

molecular targeted antineoplastic;all inhibitors;inhibitors;intermediates & fine chemicals;pharmaceuticals;chiral reagents;ly-231514

mol file:

150399-23-8.mol

usage and synthesis

chemical properties

crystalline solid

usage

pemetrexed is a novel antifolate and antimetabolite for ts, dhfr and garft with ki of 1.3 nm, 7.2 nm and 65 nm, respectively

usage

multitargeted antifolate; inhibits thymidylate synthase as well as other folate dependent enzymes. antineoplastic