Pomalidomide CAS NO.19171-19-8

product name:

4-amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione

synonyms:

3-amino-n-(2,6-dioxo-3-piperidyl)phthalimide;4-amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione;pomalidomide;pomalidomide(cc-4047);actimid;cc-4047;4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione;1h-isoindole-1,3(2h)-dione,4-amino-2-(2,6-dioxo-3-piperidinyl)-

cas:

19171-19-8

mf:

c13h11n3o4

mw:

273.24

einecs:

product categories:

inhibitor;cc-4047;inhibitors

mol file:

19171-19-8.mol

storage temp.

2-8°c

chemical properties

yellow solid

usage

pomalidomide is a thalidomide derivative, a potent inhibitor of tnf-α production. it is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma.

usage

pomalidomide is a second generation immunomodulator, tnf-α inhibitor, and thalidomide analog. an inhibitor of lps-induced tnfαrelease.

usage

pomalidomide inhibits lps-induced tnf-α release with ic50 of 13 nm