Quinapril CAS NO.85441-61-8

quinapril is an angiotensin-converting enzyme inhibitor (ace inhibitor) used in the treatment of hypertension and congestive heart failure. a prodrug, it is converted to its active metabolite, quinaprilat, in the liver.

quinapril inhibits angiotensin converting enzyme, an enzyme which catalyses the formation of angiotensin ii from its precursor,angiotensin i. angiotensin ii is a powerful vasoconstrictor and increases blood pressure through a variety of mechanisms. due to reduced angiotensin production, plasma concentrations of aldosterone are also reduced, resulting in increased excretion of sodium in the urine and increased concentrations of potassium in the blood.

quinapril is indicated for the treatment of high blood pressure (hypertension) and as adjunctive therapy in the management of heart failure. it may be used for the treatment of hypertension by itself or in combination with thiazide diuretics, and with diuretics and digoxin for heart failure.

physical and chemical properties

analytical data

hplc: 99.07% purity
nmr: consistent with structure

packaging :- 25 kg fiber drum or as per customer requirement