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Henan Tianfu Chemical Co., Ltd.Streptozotocin//www.lookchem.com/300w/2010/0619/18883-66-4.jpg
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Streptozotocin CAS NO.18883-66-4

Min.Order Quantity:
1 Kilogram
Purity:
99.0%Min
Port:
SHANGHAI
Payment Terms:
L/C,D/A,D/P,T/T,MoneyGram,Other

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Product Details

Keywords

  • 18883-66-4
  • Streptozotocin
  • Streptozocin

Quick Details

  • ProName: Streptozotocin
  • CasNo: 18883-66-4
  • Molecular Formula: C8H15N3O7
  • Appearance: off-white to pale yellow crystalline p...
  • Application: For Organic Synthesis use
  • DeliveryTime: PROMPT
  • PackAge: IN 25kg drums
  • Port: SHANGHAI
  • ProductionCapacity: 10 Metric Ton/Month
  • Purity: 99.0%Min
  • Storage: Room Temperature
  • Transportation: As Per MSDS
  • LimitNum: 1 Kilogram
  • Heavy metal: N/A
  • Grade: Industrial Grade,Food Grade,Pharma Gra...
  • Transporttation: N/A

Superiority

streptozocin basic information
product name: streptozocin
synonyms: n-(methylnitrosocarbamoyl)-a-d-glucosamine;n-(methylnitrosocarbamoyl)-alpha-d-glucosamine;n-(methylnitrosocarbamoyl)-alpha-glucosamine;stz;streptozocin;streptozotocin;str;zanosar
cas: 18883-66-4
mf: c8h15n3o7
mw: 265.22
einecs: 242-646-8
product categories: active pharmaceutical ingredients;antibiotic explorer;peptide synthesis/antibiotics;zanosar;antibiotic
mol file: 18883-66-4.mol
streptozocin structure

Details

streptozocin chemical properties
mp 121 °c (dec.)(lit.)
storage temp. −20°c
water solubility soluble
merck 13,8912
epa substance registry system d-glucose, 2-deoxy-2-[[(methylnitrosoamino) carbonyl]amino]-(18883-66-4)
safety information
hazard codes xn,t
risk statements 40-61-46-45-22-20/21/22
safety statements 36/37-53-45-36-22
ridadr 3249
wgk germany 3
rtecs lz5775000
f 3-10-21
hazardclass 6.1(b)
packinggroup iii
hazardous substances data 18883-66-4(hazardous substances data)
streptozocin usage and synthesis
chemical properties off-white to pale yellow crystalline powder
usage antineoplastic, alkylating agent
usage streptozotocin is used in the treatment metastatic cancer of the pancreatic islet cells. streptozotocin has a highlrisk of toxicity and is generally limited to cancers that are inoperable.
usage streptozotocin is an unusual aminoglycoside containing a nitrosoamino group produced by streptomyces achromogenes and discovered in 1959 as an antibiotic. the nitrosoamino group enables the metabolite to act as a nitric oxide (no) donor. no is an important messenger molecule involved in many physiological and pathological processes in the body. streptozotocin is also widely used to induce diabetes in rodent models by inhibition of β-cell o-glcnacase.
usage somatostatin octapeptide analog
general description off-white powder. melting point 115°c. used as an anti-cancer drug. carcinogenic.
air & water reactions water soluble.
reactivity profile [d-glucose, 2-deoxy-2-[[(methylnitrosoamino)-carbonyl]amino] is weakly basic. reacts exothermically with acids. reacts with both strong oxidizing agents and strong reducing agents.
biological activity antibiotic and antitumor agent. alkylates dna and induces diabetes mellitus via reduction of nicotinamide adenine dinucleotide in pancreatic β -cells in vivo .

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