clemastine fumarate basic information
product name: clemastine fumarate
synonyms: clemastine fumarate;clemastine fumarate salt;(2r)-2-[2-[(1r)-1-(4-chlorophenylethoxy)]ethyl]-1-methyl-2-pyrrolidine fumarate;(+)-2-(2-((p-chloro-alpha-methyl-alpha-phenylbenzyl)oxy)ethyl)-1-methylpyrro;(+)-2-(2-((p-chloro-alpha-methyl-alpha-phenylbenzyl)oxy)ethyl)-1-methylpyrroli;(+)-lfumarate(1:1);1-methyl-2-(2-(methyl-p-chlorodiphenylmethyloxy)ethyl)pyrrolidine;2-(2-(1-(4-chlorophenyl)-1-phenylethoxy)ethyl)-1-methylpyrrolidine
cas: 14976-57-9
mf: c25h30clno5
mw: 459.96
einecs: 239-055-2
product categories: histaminergics;antagonists;neurotransmitters;aromatics;chiral reagents;heterocycles;intermediates & fine chemicals;pharmaceuticals;tavist;antianaphylaxis
mol file: 14976-57-9.mol
clemastine fumarate structure
clemastine fumarate chemical properties
melting point 158-162°c
storage temp. store at rt
solubility dmso: soluble5mg/ml (clear solution; warmed)
color white to beige
cas database reference 14976-57-9(cas database reference)
safety information
rtecs uy0704600
hazardous substances data 14976-57-9(hazardous substances data)
msds information
provider language
(2r)-2-[2-[(1r)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine but-2-enedioic acid english
clemastine fumarate usage and synthesis
chemical properties white solid
uses h1 histamine receptor antagonist. antihistaminic.
uses anti-inflammatory
definition chebi: the fumaric acid salt of clemastine. an antihistamine with antimuscarinic and moderate sedative properties, it is used for the symptomatic relief of allergic conditions such as rhinitis, urticaria, conjunctivitis and in pruritic (severe itching) skin condi ions.
biological activity h 1 -receptor antagonist. clinically-used antihistamine.
clemastine fumarate preparation products and raw materials