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USD $2.00-10.00 / Kilogram
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our company was built in 2009 with an iso certificate.in the past 5 years, we have grown up as a famous fine chemicals supplier in china and we had established stable business relationships with samsung,lg,merck,thermo fisher scientific and so on.our main business covers the fields below:
1.noble metal catalysts (pt.pd...)
2.organic phosphine ligands (tert-butyl-phosphine.cyclohexyl-phosphine...)
3.oled intermediates (fluorene,carbazole,boric acid...)
4.customs synthesis
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abt 263 basic information |
product name: | abt 263 |
synonyms: | 4-[4-[[2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-n-[[4-[[(1r)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide;abt 263;benzamide, 4-(4-((2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl)methyl)-1-piperazinyl)-n-((4-(((1r)-3-(4-morpholinyl)-1-((phenylthio)methyl)propyl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)-;abt-263,navitoclax;navitoclax;benzamide, 4-(4-((2-(4-chlorophenyl)-5,5-dime;navitoclax (abt-263);(s)-4-(4-((4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-n-((4-((4-morpholino-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)benzamide |
cas: | 923564-51-6 |
mf: | c47h55clf3n5o6s3 |
mw: | 974.61 |
einecs: | |
product categories: | chiral reagents;inhibitors;intermediates & fine chemicals;pharmaceuticals;sulfur & selenium compounds;apis;inhibitor |
mol file: | 923564-51-6.mol |
abt 263 chemical properties |
mp | 114-116°c |
storage temp. | -20°c freezer, under inert atmosphere |
safety information |
abt 263 usage and synthesis |
chemical properties | pale yellow solid |
usage | abt-263 (navitoclax) is a potent inhibitor of bcl-xl, bcl-2 and bcl-w with ki of ≤ 0.5 nm, ≤1 nm and ≤ 1 nm, respectively. |
usage | a novel inhibitor of antiapoptotic bcl-2 proteins; a new promising anticancer drug candidate. |
abt 263 preparation products and raw materials |