Epoxide formation in the Friedel-Crafts reaction of Adipoyl chloride (cas 111-50-2) and bromobenzene
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Add time:08/20/2019 Source:sciencedirect.com
The aluminium chloride catalysed Friedel-Crafts reaction between Adipoyl chloride (cas 111-50-2) and bromobenzene has been re-examined. At elevated temperatures a number of side products are produced including a cyclopentane epoxide. The structure of this epoxide was elucidated by nmr and ir spectroscopy and its stereochemistry confirmed by x-ray crystallography.
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