Tracking of the degradation process of Chlorhexidine digluconate (cas 18472-51-0) and ethylenediaminetetraacetic acid in the presence of hyper-pure chlorine dioxide in endodontic disinfection
-
Add time:09/05/2019 Source:sciencedirect.com
Accurate knowledge of the safety of the combined use of hyper-pure chlorine dioxide (ClO2, Solumium) with different endodontic agents is not known. The objective was to investigate the possible interactions between hyper-pure ClO2 and Chlorhexidine digluconate (cas 18472-51-0) (CHX) as well as hyper-pure ClO2 and ethylenediaminetetraacetic acid (EDTA) in vitro. High-performance liquid chromatography (HPLC) was used to analyse the reaction between ClO2 and CHX for studying the possible increase of para-chloroaniline (PCA). Nuclear magnetic resonance (NMR) method was applied to investigate if the oxidising property of ClO2 inactivates EDTA. CHX itself may contain PCA; however, its amount did not increase after the mixing up with ClO2. While ClO2 did not oxidise PCA, on the other hand, it oxidised EDTA into numerous degradation products, but this reaction was slow. Hyper-pure ClO2 of excellent antimicrobial properties should be considered as a safe alternative endodontic disinfectant agent in combinations or as a final rinse. The lack of chemical interaction between ClO2 and CHX confirms their safe application in combination.
We also recommend Trading Suppliers and Manufacturers of Chlorhexidine digluconate (cas 18472-51-0). Pls Click Website Link as below: cas 18472-51-0 suppliers
Prev:Decontamination of bovine hide surfaces for enhancing food safety: Use of alkyltrimethylammonium bromide and Chlorhexidine digluconate (cas 18472-51-0)☆
Next:Chitosan/alginate complexes for vaginal delivery of Chlorhexidine digluconate (cas 18472-51-0)) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Chlorhexidine digluconate (cas 18472-51-0) as corrosion inhibitor for carbon steel dissolution in emulsified diesel fuel09/25/2019
- Is chlorhexidine-methacrylate as effective as Chlorhexidine digluconate (cas 18472-51-0) in preserving resin dentin interfaces?09/24/2019
- Original ArticleA model of Chlorhexidine digluconate (cas 18472-51-0)-induced peritoneal fibrosis in rats09/10/2019
- Dual 0.02% Chlorhexidine digluconate (cas 18472-51-0) – 0.1% disodium EDTA loaded thermosensitive ocular gel for Acanthamoeba keratitis treatment09/09/2019
- Original articleFormulation and stability of an extemporaneous 0.02% Chlorhexidine digluconate (cas 18472-51-0) ophthalmic solution09/08/2019
- Local facial atrophy and permanent anesthesia of right upper lip following subcutaneous extrusion of Chlorhexidine digluconate (cas 18472-51-0)09/07/2019
- Chitosan/alginate complexes for vaginal delivery of Chlorhexidine digluconate (cas 18472-51-0)09/06/2019
- Decontamination of bovine hide surfaces for enhancing food safety: Use of alkyltrimethylammonium bromide and Chlorhexidine digluconate (cas 18472-51-0)☆09/04/2019
- A green practice for pharmaceutical drug Chlorhexidine digluconate (cas 18472-51-0) treatment and ecotoxicity assessment09/03/2019
-
Health and Chemical more >