1.Identification

1.1 GHS Product identifier

1.2 Other means of identification

1.3 Recommended use of the chemical and restrictions on use

1.4 Supplier's details

1.5 Emergency phone number

2.Hazard identification

2.1 Classification of the substance or mixture

Acute toxicity - Oral, Category 4

Carcinogenicity, Category 2

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H351 Suspected of causing cancer H400 Very toxic to aquatic life
Precautionary statement(s)
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P280 Wear protective gloves/protective clothing/eye protection/face protection. P273 Avoid release to the environment.
Response	P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor/…if you feel unwell. P330 Rinse mouth. P308+P313 IF exposed or concerned: Get medical advice/ attention. P391 Collect spillage.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

3.Composition/information on ingredients

3.1 Substances

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

Fresh air, rest. Refer for medical attention.

In case of skin contact

Remove contaminated clothes. Rinse and then wash skin with water and soap.

In case of eye contact

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

If swallowed

Rest. Refer for medical attention .

4.2 Most important symptoms/effects, acute and delayed

SYMPTOMS: Symptoms of exposure to this compound include blurred vision, confusion, ataxia, delirium, coughing, abdominal pain, nausea, irritability and anuria. Other symptoms may include nervousness, loss of coordination, unconsciousness and dry red skin. It may also cause neuroblastoma. It is moderately irritating to the skin and can cause deep depression and liver changes. Symptoms of acute poisoning with this type of compound include vomiting, diarrhea, paraesthesia, excitement, giddiness, fatigue, tremors, convulsions, coma, possibly pulmonary edema; liver, kidney and myocardial toxicity and hypothermia. Also, respiration may be accelerated initially and later depressed. Symptoms of chronic poisoning with this type of compound may include headache, loss of appetite, muscular weakness, fine tremors, apprehensive mental state, aplastic anemia and acute leukemia. ACUTE/CHRONIC HAZARDS: This compound is readily absorbed through the skin as well as through other portals. It is toxic by skin absorption and orally. When heated to decomposition it emits toxic fumes of organo chloride products, carbon monoxide and carbon dioxide.

Fatal oral dose to adult humans is between 6 and 60 g with onset of symptoms within 45 minutes to several hours after ingestion, although symptoms have occurred following very small doses either orally or by skin exposure. Some reports of delayed development of liver disease, blood disorders and upset stomach. Chlordane is considered to be borderline between a moderately and highly toxic substance. (EPA, 1998)

4.3 Indication of immediate medical attention and special treatment needed, if necessary

Treatment is symptomatic and supportive. Oils should not be used as either cathartics or dermal cleansing agents, as they increase absorption. Gastric lavage and use of activated charcoal and sodium sulfate are indicated for ingestion. If dermal exposure occurred, contaminated clothes should be removed, and the skin should be thoroughly cleansed with soap and water. Management of seizures in both children and adults is with Valium or phenobarbital. Respiratory depression and even respiratory arrest, especially with concomitant use of Valium and phenobarbital in children, may occur. These drugs preferably should be used only in critical care areas where emergency endotracheal intubation can be performed. /It is recommended/ that epinephrine not be utilized in patients with organochlorine poisoning, as the organochlorines induce myocardial irritability and ventricular arrhythmias may occur. However, dopamine may be necessary in the event of hypotension unresponsive to fluid administration, and epinephrine may be necessary in the event of cardiopulmonary arrest. ... /Organochlorine insecticides/

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

Fire fighting: Self-contained breathing apparatus with a full facepiece, operated in pressure-demand or other positive-pressure mode. ...

5.2 Specific hazards arising from the chemical

This chemical is combustible.

Flammable/combustible material; may be ignited by heat, sparks or flames. Vapors may travel to a source of ignition and flash back. Run-off to sewers may create fire or explosion hazard. Containers may explode in heat of fire. Vapors are toxic indoors and outdoors. Chlordane degrades under natural environmental conditions to photoisomers, such as photo-cis- chlordane, which are more toxic to certain animals than chlordane and also showed higher bioaccumulation. Loses chlorine in presence of alkaline reagents; should not be formulated with any solvent, carrier, diluent or emulsifier which has alkaline reaction. (EPA, 1998)

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer. Personal protection: chemical protection suit including self-contained breathing apparatus.

6.3 Methods and materials for containment and cleaning up

A process for removing pollutants from Du pont's chambers works plant in Deepwater, NJ is described. Process involves neutralization of wastes & settling, followed by combined powdered carbon-biological process. Among pesticides listed as priority pollutants are heptachlor and chlordane.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs, bases and incompatible materials. See Chemical Dangers. Well closed. Keep in a well-ventilated room.Ambient temperature for storage.

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

NIOSH considers chlordane to be a potential occupational carcinogen. NIOSH usually recommends that occupational exposures to carcinogens be limited to the lowest feasible concn.

Recommended Exposure Limit: 10 Hr Time-Weighted Avg: 0.5 mg/cu m, skin.

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

Dehydrohalogenates in presence of alkali

10.3 Possibility of hazardous reactions

CHLORDANE, a mixture of related chlorinated cyclodienes, is decomposed by alkalis. Corrodes iron and zinc. Can react with strong oxidizing agents. Attacks some forms of plastics, rubber and coatings

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

Loses ...chlorine in presence of alkaline reagents and should not be formulated with any solvent, carrier, diluent or emulsifier, which has alkaline reaction.

10.6 Hazardous decomposition products

Hazardous decomposition products: Toxic gases and vapors, such as hydrogen chloride, chlorine, phosgene, and carbon monoxide. ...

11.Toxicological information

Acute toxicity

• Oral: LD50 Rat oral 590 mg/kg
• Inhalation: LC50 Cat inhalation 100 mg/cu m/4 hours
• Dermal: LD50 Rat (female) percutaneous 690 mg/kg

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

EPA: Probable human carcinogen, IARC: Not classifiable as to carcinogenicity to humans, NTP: Not evaluated

Reproductive toxicity

A study of women living in homes repeatedly treated for termites with chlordane revealed an increased incidence of ovarian and uterine disease, compared with a reference population. However, it is not possible to state whether these effects were solely due to chlordane or to other chemicals as well. An animal study reported biochemical and behavioral laterations mimicking male sex steroids, while another study reported alterations in reproductive behavior, both in male rats exposed to chlordane.

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

• Toxicity to fish: LC50 Rainbow trout 42 ug/l/96 hr (95% confidence limit 37-48 ug/l) @ 12°C, wt 1.0 g. Static bioassay without aeration, pH 7.2-7.5, water hardness 40-50 mg/l as calcium carbonate and alkalinity of 30-35 mg/l.
• Toxicity to daphnia and other aquatic invertebrates: no data available
• Toxicity to algae: no data available
• Toxicity to microorganisms: no data available

12.2 Persistence and degradability

A pure culture of Nocardiopsis sp. isolated from soil was able to degrade chlordane with dichlorochlordene, oxychlordane, heptachlor, heptachlor-endo-epoxide, chlordene, chlorohydrin, and 3-hydroxy-trans-chlordene produced as metabolites(1).

12.3 Bioaccumulative potential

Lagodon rhomboides (pinfish) exposed to chlordane exhibited a bioconcentration factor of 6227. Duration of 96 hr.

12.4 Mobility in soil

The extremely low mobility of chlordane within soil ... after 14 months and 72 inches (183 cm) of rainfall /was observed/. Chlordane was found not to have extensively penetrated below nine inches (23 cm). Most of the residues (85-90%) were found in the 0-3 inch (0-8 cm) cultivated layer. Nine to 15% and 1.2-1.6% were found in the 3-6 inch (8-15 cm) and 6-9 inch (15-23 cm) layers, respectively.

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

14.2 UN Proper Shipping Name

14.3 Transport hazard class(es)

14.4 Packing group, if applicable

14.5 Environmental hazards

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

16.Other information

Information on revision

Abbreviations and acronyms

• CAS: Chemical Abstracts Service
• ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
• RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
• IMDG: International Maritime Dangerous Goods
• IATA: International Air Transportation Association
• TWA: Time Weighted Average
• STEL: Short term exposure limit
• LC50: Lethal Concentration 50%
• LD50: Lethal Dose 50%
• EC50: Effective Concentration 50%

References

• IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
• HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
• IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
• eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
• CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
• ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
• ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
• Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
• ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.