Enzyme-catalyzed kinetic resolution of 1,3-anti-diol monoesters - Efficient preparation of enantiomerically highly enriched and unsymmetrically substituted 1,3-anti-diols
Candida antarctica Lipase B (CALB) catalyzed the highly enantioselective acetylation of 1,3-anti-diol monoesters which have been obtained through a zirconium-catalyzed aldol-Tishchenko reaction. The product 1,3-anti-diol diesters were formed in yields clo