174072-89-0Relevant articles and documents
Five-membered nitrogen-containing heteroaryl substituted pyrimidinedione compound and application thereof
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Paragraph 0131; 0137-0141, (2021/01/15)
The invention belongs to the technical field of medicines, and relates to a five-membered nitrogen-containing heteroaryl substituted pyrimidinedione compound and application thereof, and a pharmaceutical composition containing the five-membered nitrogen-containing heteroaryl substituted pyrimidinedione compound, and the five-membered nitrogen-containing heteroaryl substituted pyrimidinedione compound and the pharmaceutical composition can be used as gonadotropin releasing hormone receptor antagonists. The invention also relates to a method for preparing the compound and the pharmaceutical composition, and application of the compound and the pharmaceutical composition in prevention or treatment of sex hormone dependent diseases including but not limited to prostate cancer, endometriosis, hysteromyoma, precocious puberty and the like.
Phenyl-substituted thieno[2,3-d]pyrimidine-2,4 (1H,3H)-dione compounds and application thereof
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Paragraph 0143; 0149-0153, (2020/09/09)
The invention belongs to the technical field of medicines, and relates to phenyl-substituted thieno[2,3-d]pyrimidine-2,4 (1H,3H)-dione compounds, application thereof, and a pharmaceutical compositioncontaining the compounds. The compounds and the pharmaceutical composition can be used as gonadotropin releasing hormone receptor antagonists. The invention also relates to a method for preparing thecompounds and the pharmaceutical composition, and application of the compounds and the pharmaceutical composition in prevention or treatment of sex hormone dependent diseases including but not limitedto prostate cancer, endometriosis, hysteromyoma, precocious puberty and the like.
Nitrogen-containing heteroaryl substituted pyrimidinedione compound and application thereof
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Paragraph 0130; 0135; 0140-0145, (2020/11/25)
The invention belongs to the technical field of medicines, and relates to a nitrogen-containing heteroaryl substituted pyrimidinedione compound and application thereof, and a pharmaceutical composition containing the compound, and the nitrogen-containing heteroaryl substituted pyrimidinedione compound and the pharmaceutical composition can be used as gonadotropin releasing hormone receptor antagonists. The invention also relates to a method for preparing the compound and the pharmaceutical composition, and application of the compound and the pharmaceutical composition in prevention or treatment of sex hormone dependent diseases including but not limited to prostate cancer, endometriosis, hysteromyoma, precocious puberty and the like.