252049-06-2 Usage
General Description
FMOC-N-ME-THR-OH is a chemical compound that belongs to the class of amino acids and derivatives. It is a derivative of threonine, an essential amino acid that plays a crucial role in protein synthesis and various metabolic processes in the body. FMOC-N-ME-THR-OH is often used in organic chemistry and biochemistry research as a building block for the synthesis of peptides and proteins. Its FMOC (fluorenylmethyloxycarbonyl) group serves as a protecting group for the threonine amino acid, allowing for selective modification and manipulation of the amino acid in the synthesis of complex molecules. Overall, FMOC-N-ME-THR-OH is an important chemical compound in the field of chemical and biological research, serving as a key component in the development of various peptide-based drugs and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 252049-06-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,2,0,4 and 9 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 252049-06:
(8*2)+(7*5)+(6*2)+(5*0)+(4*4)+(3*9)+(2*0)+(1*6)=112
112 % 10 = 2
So 252049-06-2 is a valid CAS Registry Number.
252049-06-2Relevant articles and documents
An improved synthesis of Fmoc-N-methyl serine and threonine
Bahekar, Rajesh H.,Jadav, Pradip A.,Patel, Dipam N.,Prajapati, Vijay M.,Gupta, Arun A.,Jain, Mukul R.,Patel, Pankaj R.
, p. 5003 - 5005 (2007)
An improved method for the synthesis of Fmoc-N-methyl serine and threonine has been developed, which involves formation and subsequent reduction of the corresponding oxazolidinone with a Lewis acid under mild conditions, with improved yields and shorter reaction times.
Synthesis, stereochemical assignment, and bioactivity of the Penicillium metabolites penicillenols B1 and B2
Kempf, Karl,Schmitt, Florian,Bilitewski, Ursula,Schobert, Rainer
, p. 5064 - 5068 (2015/06/25)
The Penicillium metabolites penicillenols B1 and B2 were synthesised for the first time by elimination of a mesylated penicillenol A precursor as obtained from an l-threonine derived tetramic acid. The (Z,S)- and (E,S)-configured diastereomers were identical to the natural compounds as to NMR spectra and optical rotations. Both isomers showed antiproliferative effects against cancer and endothelial cell lines and penicillenol B1 was also notably antibiotic against Staphylococcus aureus.