56074-20-5Relevant articles and documents
Trifunctional reagents for substrate-protein conjugation: Application to pyrrolizidine alkaloid analogues
Kurth,Milco,Miller
, p. 1407 - 1416 (1992)
We report the syntheses of two pyrrolizidine alkaloid (PA) analogues (1 and 2) which exploit the novel substrate-protein coupling reagents 4 and 5. Analogues 1 and 2 incorporate the targeted PA substructural unit (i.e., a macrocyclic diester of retronecine), possess a handle for protein conjugation, and potentially maintain the conformational integrity of macrocyclic PAs.
Design, synthesis and evaluation of novel bifunctional tetrahydroxamate chelators for PET imaging of89Zr-labeled antibodies
Rousseau, Julie,Zhang, Zhengxing,Dias, Gemma M.,Zhang, Chengcheng,Colpo, Nadine,Bénard, Fran?ois,Lin, Kuo-Shyan
, p. 708 - 712 (2017)
Two compact and symmetrical bifunctional tetrahydroxamate chelators, 1 and 2, were synthesized and evaluated for labeling antibodies with89Zr for imaging with positron emission tomography. Using 2,2′-iminodiacetamide as the backbone, four hydro
Selective Extraction and Complexation Studies for Thorium(IV) with Bis-triamide Extractants: Synthesis, Solvent Extraction, EXAFS, and DFT
Kang, Jinyang,Wu, Rulei,Li, Long,Hu, Haiyang,Fan, Yu,Jin, Yongdong,Huang, Chao,Chen, Jing,Xu, Chao,Xia, Chuanqin
, p. 14212 - 14220 (2021/09/20)
Three octyl-extended bis-triamide extractants (L1-L3) were designed and synthesized for the selective solvent extraction of Th(IV) over U(VI) in a kerosene-HNO3system. L1 and L2 exhibited good extraction property and selectivity toward Th(IV) o
IONIZABLE CATIONIC LIPID FOR RNA DELIVERY
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Paragraph 0734; 0735; 0736; 0737, (2018/07/05)
What is described is a compound of formula I consisting of a compound in which R1 is a branched chain alkyl consisting of 10 to 31 carbons;R2 is a linear alkyl, alkenyl, or alkynyl consisting of 2 to 20 carbons, or a branched chain alkyl consisting of 10 to 31 carbons;L1 and L2 are the same or different, each a linear alkane of 1 to 20 carbons or a linear alkene of 2 to 20 carbons;X1 is S or O;R3 is a linear or branched alkylene consisting of 1 to 6 carbons; andR4 and R5 are the same or different, each a hydrogen or a linear or branched alkyl consisting of 1 to 6 carbons; or a pharmaceutically acceptable salt thereof.