6205-08-9 Usage
Description
N-ALPHA-ACETYL-L-ORNITHINE is a chemical compound derived from L-ornithine, an amino acid found in the body. It is characterized by the addition of an acetyl group to the alpha nitrogen atom of L-ornithine, which alters its properties and potential applications.
Uses
Used in Medical Research:
N-ALPHA-ACETYL-L-ORNITHINE is used as a biomarker for the identification of type 2 diabetes group through topological analysis of patient similarity. This application aids in the diagnosis and understanding of the disease's progression, potentially leading to more effective treatments and interventions.
Biochem/physiol Actions
Nα-Acetyl-L-ornithine (AORN) is a substrate for the identification, differentiation and characterization of N(α)-acetyl-L-ornithine deacetylase(s) and of N-Acetyl-l-ornithine transcarbamylase(s) (AOTCase) found in plants, some eubacteria and some human pathogens.
Check Digit Verification of cas no
The CAS Registry Mumber 6205-08-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,0 and 5 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 6205-08:
(6*6)+(5*2)+(4*0)+(3*5)+(2*0)+(1*8)=69
69 % 10 = 9
So 6205-08-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H14N2O3/c1-5(10)9-6(7(11)12)3-2-4-8/h6H,2-4,8H2,1H3,(H,9,10)(H,11,12)/t6-/m0/s1
6205-08-9Relevant articles and documents
Preparation of N alpha-acetylornithine.
THOMPSON,GERING
, p. 326 - 327 (1962)
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Inhibitors of N α-acetyl-l-ornithine deacetylase: Synthesis, characterization and analysis of their inhibitory potency
Hlavacek,Picha,Vanek,Jiracek,Slaninova,Fucik,Budesinsky,Gilner,Holz
experimental part, p. 1155 - 1164 (2010/08/06)
A series of N α-acyl (alkyl)- and N α- alkoxycarbonyl-derivatives of l- and d-ornithine were prepared, characterized, and analyzed for their potency toward the bacterial enzyme N α-acetyl-l-ornithine deacetylase (ArgE). Ar
Cosmetic composition
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, (2008/06/13)
A composition suitable for topical application to mammalian skin and hair for inducing, maintaining or increasing hair growth comprises a hair growth promoter chosen from glutamine derivatives and salts thereof. The composition preferably also comprises an activity enhancer which may be chosen from hair growth stimulants, penetration enhancers and cationic polymers.