78537-14-1

Basic information

• Product Name: O-tert-Butyl-D-serine methyl ester hydrochloride
• Synonyms: O-TERT-BUTYL-D-SERINE METHYL ESTER HYDROCHLORIDE;O-T-BUTYL-D-SERINE METHYL ESTER HYDROCHLORIDE;O-T-BUTYL-D-SERINE METHYL ESTER HYDROCHLORIDE SALT;H-D-SER(BUT)-OME HCL;H-D-SER(TBU)-OME HCL;D-SERINE(TBU)-OME HCL;H-D-Ser(tBu)-OMe.HCI;D-(O-tert-Bu)-Ser-OMehydrochloride
• CAS NO: 78537-14-1
• Molecular Formula: C₈H₁₇NO₃*ClH
• Molecular Weight: 211.69
• EINECS: 1533716-785-6
• Product Categories: Amino Acids;Amino Acids and Derivatives;Amino Acid Derivatives
• Mol File: 78537-14-1.mol
• Article Data: 0

Chemical Properties

• Appearance: White/Powder
• Storage Temp.: 2-8°C
• CAS DataBase Reference: O-tert-Butyl-D-serine methyl ester hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: O-tert-Butyl-D-serine methyl ester hydrochloride(78537-14-1)
• EPA Substance Registry System: O-tert-Butyl-D-serine methyl ester hydrochloride(78537-14-1)

Safety Data

• Hazardous Substances Data: 78537-14-1(Hazardous Substances Data)

Usage

Description

O-tert-Butyl-D-serine methyl ester hydrochloride is a synthetic organic compound that serves as a crucial building block in the synthesis of various pharmaceuticals and bioactive molecules. It is characterized by its unique structure, which includes a tert-butyl group, a D-serine backbone, and a methyl ester functional group, along with a hydrochloride counterion. O-tert-Butyl-D-serine methyl ester hydrochloride plays a significant role in the development of opioid peptides and other therapeutic agents.

Uses

Used in Pharmaceutical Industry:
O-tert-Butyl-D-serine methyl ester hydrochloride is used as a key intermediate in the synthesis of opioid peptides for the development of potent agonists targeting the δ opioid receptors. These agonists are crucial in the management of pain and have potential applications in treating various chronic and acute pain conditions.
Used in Peptide Synthesis:
As a reagent, O-tert-Butyl-D-serine methyl ester hydrochloride is employed in the preparation of peptide-based therapeutics. Its unique structure allows for the efficient synthesis of complex peptide sequences, which can be further modified or functionalized to create novel bioactive molecules with specific therapeutic properties.
Used in Drug Development:
O-tert-Butyl-D-serine methyl ester hydrochloride contributes to the advancement of drug discovery and development by providing a versatile and reliable starting material for the creation of new pharmaceutical agents. Its use in the synthesis of opioid peptides highlights its potential in developing innovative treatments for pain management and other medical conditions.

Downstream Products

• 78537-17-4 N-(tert-butyloxycarbonyl)-L-tyrosyl-O-tert-butyl-D-serylglycyl-L-phenylalanyl-L-leucyl-O-tert-butyl-L-threonine methyl ester 
• 78537-18-5 N-(tert-butyloxycarbonyl)-L-tyrosyl-O-tert-butyl-D-serylglycyl-L-phenylalanyl-L-leucyl-O-tert-butyl-L-threonine 
• 78537-16-3 N-(tert-butyloxycarbonyl)-L-tyrosyl-O-tert-butyl-D-serylglycyl-L-phenylalanyl-L-leucine methyl ester 
• 78565-55-6 N-(tert-butyloxycarbonyl)-L-tyrosyl-O-tert-butyl-D-serylglycyl-L-phenylalanyl-L-leucine 
• 115141-32-7 N-(benzyloxycarbonyl)-L-tyrosyl-O-tert-butyl-D-serylglycyl-L-phenylalanyl-L-leucyl-L-threonine benzyl ester 
• 114442-56-7 N-(benzyloxycarbonyl)-L-tyrosyl-O-tert-butyl-D-serylglycyl-L-phenylalanyl-L-leucyl-O-t-butyl-L-threonine 
• 114414-60-7 Tyr-D-Ser(O-t-Bu)-Gly-Phe-Leu-Thr(O-t-Bu) 
• 111035-56-4 Tyr-D-Ser(O-t-Bu)-Gly-Phe-Leu-Thr 
• 115141-30-5 {(R)-2-[(S)-2-Benzyloxycarbonylamino-3-(4-hydroxy-phenyl)-propionylamino]-3-tert-butoxy-propionylamino}-acetic acid methyl ester 
• 114414-62-9 N-(benzyloxycarbonyl)-L-tyrosyl-O-tert-butyl-D-seryl-glycine 
• 114414-63-0 N-(benzyloxycarbonyl)-L-tyrosyl-O-tert-butyl-D-seryne 
• 256666-11-2 phenethylsulfonyl-DSer(O-t-Bu)-OH 
• 78537-13-0 N-(tert-butyloxycarbonyl)-L-tyrosyl-O-tert-butyl-D-serine methyl ester 
• 115141-44-1 Cbz-Tyr-D-Ser(t-Bu)-OMe