91237-84-2 Usage
Description
Boc-L-PyroglutamicAcidTert-ButylEster is a chemical compound derived from pyroglutamic acid, a naturally occurring amino acid found in various proteins and peptides. It is commonly used in organic synthesis and pharmaceutical research as a building block for the synthesis of new drugs and pharmaceutical compounds due to its stability and ease of manipulation.
Uses
Used in Pharmaceutical Research:
Boc-L-PyroglutamicAcidTert-ButylEster is used as a protecting group in chemical synthesis to prevent unwanted reactions. It can be deprotected to reveal the free amine group for further functionalization, playing a crucial role in the development of novel pharmaceuticals and bioactive compounds.
Used in Organic Synthesis:
Boc-L-PyroglutamicAcidTert-ButylEster is used as a building block for the synthesis of new compounds, contributing to the advancement of organic chemistry and the creation of innovative materials and products.
Check Digit Verification of cas no
The CAS Registry Mumber 91237-84-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,2,3 and 7 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 91237-84:
(7*9)+(6*1)+(5*2)+(4*3)+(3*7)+(2*8)+(1*4)=132
132 % 10 = 2
So 91237-84-2 is a valid CAS Registry Number.
91237-84-2Relevant articles and documents
Practical one-pot double functionalizations of proline
Huy, Peter,Schmalz, Hans-Guenther
body text, p. 954 - 960 (2011/05/07)
Solubilization of proline as the triethylammonium salt allows N-protection (as the Boc, Cbz or Moc derivative) and subsequent esterification or amidation of the carboxy terminus to be performed in an efficient one-pot fashion. Based on this concept, highly practical protocols were developed to prepare a series of proline derivatives (including Pro-Ser dipetides, Weinreb amides and N-protected proline esters), which are important intermediates, for instance, for the synthesis of proline-derived peptides, chiral reagents and catalysts for asymmetric synthesis. Georg Thieme Verlag Stuttgart - New York.