4-N,4-N-dicyclohexylbenzene-1,4-dicarboxamide

Base Information

• Chemical Name: 4-N,4-N-dicyclohexylbenzene-1,4-dicarboxamide
• CAS No.: 15088-29-6
• Molecular Formula: C20H28 N2 O2
• Molecular Weight: 328.455
• DSSTox Substance ID: DTXSID90355197
• Wikidata: Q82133937
• Mol file: 15088-29-6.mol

Synonyms:CBMicro_048206;4-N,4-N-dicyclohexylbenzene-1,4-dicarboxamide;Cambridge id 5306473;Oprea1_529181;N'-dicyclohexylterephthalamide;SCHEMBL812387;DTXSID90355197;AKOS032947945;BIM-0048086.P001;SR-01000520103;SR-01000520103-1

Chemical Property of 4-N,4-N-dicyclohexylbenzene-1,4-dicarboxamide

Chemical Property:

• Boiling Point: 571.4°Cat760mmHg
• PKA: 13.70±0.20(Predicted)
• Flash Point: 196.8°C
• PSA: 58.20000
• Density: 1.12g/cm³
• LogP: 4.59340
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 328.215078140
• Heavy Atom Count: 24
• Complexity: 413

Purity/Quality:

99% ^*data from raw suppliers

N1,N4-Dicyclohexylterephthalamide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1CCC(CC1)N(C2CCCCC2)C(=O)C3=CC=C(C=C3)C(=O)N

Technology Process of 4-N,4-N-dicyclohexylbenzene-1,4-dicarboxamide

There total 5 articles about 4-N,4-N-dicyclohexylbenzene-1,4-dicarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.4%

1,4-benzenedicarboxylic acid dimethyl ester (120-61-6) + cyclohexylamine (108-91-8,157973-60-9) → N,N'-dicyclohexyl-1,4-benzenedicarboxamide (15088-29-6)

Guidance literature:

With pyridine; potassium carbonate; at 135 ℃; for 30h; Temperature; Pressure; Reagent/catalyst;

Reference yield: 85.6%

cyclohexylamine (108-91-8,157973-60-9) + terephthaloyl chloride (100-20-9) → N,N'-dicyclohexyl-1,4-benzenedicarboxamide (15088-29-6)

Guidance literature:

With pyridine; triethylamine; In N,N-dimethyl-formamide; toluene; at 50 ℃; for 5h;

Reference yield: 58.0%

terephthalic acid (100-21-0) + cyclohexylamine (108-91-8,157973-60-9) → N,N'-dicyclohexyl-1,4-benzenedicarboxamide (15088-29-6)

Guidance literature:

With triethylamine; benzenesulfonyl chloride; In acetone; at 20 - 23 ℃; for 0.0833333h;

upstream raw materials:

cyclohexylamine

terephthaloyl chloride

cyclohexylamine hydrochloride

terephthalic acid

Downstream raw materials:

1,4-benzenebis(N,N′-dicyclohexylamidine)

Refernces

• 1、 -. "POLYETHYLENE COMPOSITIONS WITH IMPROVED OPTICAL PROPERTIES". Paragraph 0026-0027. . Retrieved 2018/02/28.
• 2、 -. "A method for the production of nucleator-amide". Paragraph 0031-0033. . Retrieved 2018/02/04.