C₂₄H₁₅Cl

Base Information

• Chemical Name: C₂₄H₁₅Cl
• CAS No.: 1310543-32-8
• Molecular Formula: C₂₄H₁₅Cl
• Molecular Weight: 338.836
• Mol file: 1310543-32-8.mol

Synonyms:C₂₄H₁₅Cl

Chemical Property of C₂₄H₁₅Cl

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₁₅Cl

There total 5 articles about C₂₄H₁₅Cl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

3-chloro-8-bromobenzo[c]phenanthrene (1310543-31-7) + phenylboronic acid (98-80-6) → C24H15Cl (1310543-32-8)

Guidance literature:

With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In ethanol; water; toluene; at 90 ℃; for 4h; Inert atmosphere;

Reference yield:

1-bromo-4-(4-chloro-2-formylphenyl)naphthalene (1310543-29-3) → C24H15Cl (1310543-32-8)

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium tert-butylate / diethyl ether; tetrahydrofuran / 1 h / 20 °C / Inert atmosphere

1.2: 4 h / 20 °C / Inert atmosphere

2.1: methanesulfonic acid / dichloromethane / 4 h / 20 °C / Inert atmosphere

3.1: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene; ethanol; water / 4 h / 90 °C / Inert atmosphere

With methanesulfonic acid; potassium tert-butylate; sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; diethyl ether; ethanol; dichloromethane; water; toluene; 3.1: Suzuki-Miyaura coupling;

Reference yield:

1-iodo-4-bromo-naphthalene (63279-58-3) → C24H15Cl (1310543-32-8)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene; ethanol; water / 2.5 h / Inert atmosphere; Reflux

2.1: potassium tert-butylate / diethyl ether; tetrahydrofuran / 1 h / 20 °C / Inert atmosphere

2.2: 4 h / 20 °C / Inert atmosphere

3.1: methanesulfonic acid / dichloromethane / 4 h / 20 °C / Inert atmosphere

4.1: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene; ethanol; water / 4 h / 90 °C / Inert atmosphere

With methanesulfonic acid; potassium tert-butylate; sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; diethyl ether; ethanol; dichloromethane; water; toluene; 1.1: Suzuki-Miyaura coupling / 4.1: Suzuki-Miyaura coupling;

upstream raw materials:

3-chloro-8-bromobenzo[c]phenanthrene

phenylboronic acid

1-iodo-4-bromo-naphthalene

4-chloro-2-aldehyde phenylboronic acid

Downstream raw materials:

C₃₀H₂₇BO₂

Refernces