Pyrrolidine-2-carboxamide hydrochloride

Base Information

• Chemical Name: Pyrrolidine-2-carboxamide hydrochloride
• CAS No.: 115630-49-4
• Molecular Formula: C5H11ClN2O
• Molecular Weight: 150.608
• DSSTox Substance ID: DTXSID40388490
• Mol file: 115630-49-4.mol

Synonyms:115630-49-4;pyrrolidine-2-carboxamide hydrochloride;H-DL-Pro-NH2.HCl;2-Pyrrolidinecarboxamide HCl;Pyrrolidine-2-carboxamide HCl;2-Pyrrolidinecarboxamide, monohydrochloride;pyrrolidine-2-carboxamide;hydrochloride;H-D-Pro-NH2.HCl;2-PYRROLIDINECARBOXAMIDE HYDROCHLORIDE;H-Pro-NH HCl;H-D-Pro-NH HCl;H-Pro-NH2.HCl;dl-prolinamide hydrochloride;H-DL-Pro-NH2 . HCl;SCHEMBL241228;DTXSID40388490;CSKSDAVTCKIENY-UHFFFAOYSA-N;MFCD00237860;AKOS015849680;CS-W005850;DS-1703;SB21919;H-DL-Pro-NH2 hydrochloride, AldrichCPR;DL-Pyrrolidine-2-carboxamide hydrochloride;2-Pyrrolidinecarboxamide,hydrochloride(1:1);FT-0627591;FT-0681496;FT-0693268;EN300-43072;2-Pyrrolidinecarboxamide, hydrochloride (1:1);F10562;pyrrolidine-2-carboxylic acid amide hydrochloride;A803461

Chemical Property of Pyrrolidine-2-carboxamide hydrochloride

Chemical Property:

• Vapor Pressure: 0.000923mmHg at 25°C
• Refractive Index: 1.491
• Boiling Point: 303.6 °C at 760 mmHg
• Flash Point: 137.4 °C
• PSA: 55.12000
• Density: 1.106g/cm³
• LogP: 1.05480
• Storage Temp.: Store at 0°C
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 150.0559907
• Heavy Atom Count: 9
• Complexity: 103

Purity/Quality:

99% ^*data from raw suppliers

DL-ProlinamideHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(NC1)C(=O)N.Cl

Technology Process of Pyrrolidine-2-carboxamide hydrochloride

There total 1 articles about Pyrrolidine-2-carboxamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ proline amide hydrochloride (115630-49-4,50894-62-7)

Guidance literature:

Reference yield: 62.0%

proline amide hydrochloride (115630-49-4,50894-62-7) + di-tert-butyl dicarbonate (24424-99-5) → tert-butyl 2-carbamoylpyrrolidine-1-carboxylate (54503-10-5)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 16h;

Reference yield:

proline amide hydrochloride (115630-49-4,50894-62-7) + C21H19N3O5S3 → 1-(3-(N-(4-(3-phenylisoxazol-5-yl)thiazol-2-yl)thiophene-2-carboxamido)propyl)pyrrolidine-2-carboxamide (1006872-68-9)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In 1-methyl-pyrrolidin-2-one; at 20 ℃;

Downstream raw materials:

tert-butyl 2-carbamoylpyrrolidine-1-carboxylate

1-(3-(N-(4-(3-phenylisoxazol-5-yl)thiazol-2-yl)thiophene-2-carboxamido)propyl)pyrrolidine-2-carboxamide

Refernces