Methylenedioxypyrovalerone

Base Information

• Chemical Name: Methylenedioxypyrovalerone
• CAS No.: 687603-66-3
• Molecular Formula: C16H21NO3
• Molecular Weight: 275.34
• UNII: E7LD6JMR0L
• DSSTox Substance ID: DTXSID90897461
• Nikkaji Number: J2.658.826J
• Wikidata: Q417010
• Wikipedia: Methylenedioxypyrovalerone
• Mol file: 687603-66-3.mol

Synonyms:((R,S)-MDPV));(3,4)-methylenedioxypyrovalerone;3,4-methylenedioxypyrovalerone;Bath Salts, Psychoactive;Cathinones, Synthetic;MDPV;MDPV compound;methylenedioxypyrovalerone;Psychoactive Bath Salts;Salts, Psychoactive Bath;Synthetic Cathinone;Synthetic Cathinones

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of Methylenedioxypyrovalerone

Chemical Property:

• Appearance/Colour: white powder
• Melting Point: 209.3 °C (409 °F)
• Boiling Point: 415.5 °C at 760 mmHg
• PKA: 8.41±0.20(Predicted)
• Flash Point: 205.1 °C
• PSA: 38.77000
• Density: 1.169 g/cm³
• LogP: 2.80040
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 275.15214353
• Heavy Atom Count: 20
• Complexity: 341

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCC(C(=O)C1=CC2=C(C=C1)OCO2)N3CCCC3
• Uses: Stimulant Drug

Technology Process of Methylenedioxypyrovalerone

There total 6 articles about Methylenedioxypyrovalerone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R/S)-1-((benzo[d][1,3]dioxol-5-yl)-2-(pyrrolidin-1-yl)pentan-1-one) hydrochloride (24622-62-6) → MDPV (687603-66-3)

Guidance literature:

With sodium carbonate; In diethyl ether; water; at 20 ℃;

DOI:10.1002/chir.22423

Reference yield:

piperonal (120-57-0,30024-74-9) → MDPV (687603-66-3)

Guidance literature:

Multi-step reaction with 4 steps

1: tetrahydrofuran / 0.5 h / 5 - 20 °C / Inert atmosphere

2: manganese(IV) oxide / chloroform; tetrahydrofuran / 1 h / Reflux

3: bromine / chloroform / 20 °C

4: diethyl ether / 0 - 20 °C

With manganese(IV) oxide; bromine; In tetrahydrofuran; diethyl ether; chloroform; 1: |Grignard Reaction;

DOI:10.1002/chir.22423

Reference yield:

1-(benzo[d][1,3]dioxol-5-yl)pentan-1-ol (5422-01-5) → MDPV (687603-66-3)

Guidance literature:

Multi-step reaction with 3 steps

1: manganese(IV) oxide / chloroform; tetrahydrofuran / 1 h / Reflux

2: bromine / chloroform / 20 °C

3: diethyl ether / 0 - 20 °C

With manganese(IV) oxide; bromine; In tetrahydrofuran; diethyl ether; chloroform;

DOI:10.1002/chir.22423

upstream raw materials:

piperonal

1-(benzo[d][1,3]dioxol-5-yl)pentan-1-ol

1-(benzo[d]-1,3-dioxol-5-yl)pentan-1-one

pyrrolidine

Downstream raw materials:

(R/S)-1-((benzo[d][1,3]dioxol-5-yl)-2-(pyrrolidin-1-yl)pentan-1-one) hydrochloride

Refernces