Methyl DL-lysinate dihydrochloride

Base Information

• Chemical Name: Methyl DL-lysinate dihydrochloride
• CAS No.: 34015-48-0
• Molecular Formula: C₇H₁₇N₂O₂*Cl
• Molecular Weight: 196.677
• European Community (EC) Number: 251-794-2
• Mol file: 34015-48-0.mol

Synonyms:Methyl DL-lysinate dihydrochloride;34015-48-0;DL-lysine methyl ester dihydrochloride;methyl 2,6-diaminohexanoate dihydrochloride;methyl 2,6-diaminohexanoate;dihydrochloride;H-D-Lys-OMe.2HCl;MFCD08275416;(S)-methyl 2,6-diaminohexanoate dihydrochloride;Methyl DL-lysinate HCl;SCHEMBL1518095;EINECS 251-794-2;MFCD03547976;AKOS024374949;d,l-lysine methyl ester dihydrochloride;HY-W141971;LS-13390;SY109036;CS-0201761;L0228;G69117;methyl 2,6-bis(azanyl)hexanoate dihydrochloride;A818401;2,6-diaminohexanoic acid methyl ester dihydrochloride

Chemical Property of Methyl DL-lysinate dihydrochloride

Chemical Property:

• Melting Point: 211 °C(dec.)
• Boiling Point: 243.9°Cat760mmHg
• Flash Point: 93.5°C
• PSA: 24.39000
• Density: g/cm³
• LogP: 3.51400
• Water Solubility.: Soluble in water
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 232.0745332
• Heavy Atom Count: 13
• Complexity: 117

Purity/Quality:

99% ^*data from raw suppliers

DL-Lysine Methyl Ester Dihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)C(CCCCN)N.Cl.Cl

Technology Process of Methyl DL-lysinate dihydrochloride

There total 18 articles about Methyl DL-lysinate dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + L-Lysine hydrochloride (657-27-2,10098-89-2,26124-78-7) → lysine methyl ester dihydrochloride (13515-95-2,15445-34-8,26348-70-9,34015-48-0,67396-08-1,130336-19-5)

Guidance literature:

With thionyl chloride; for 17h; Reflux;

DOI:10.1016/j.tetlet.2015.12.070

Reference yield: 100.0%

methanol (67-56-1) + L-lysine (56-87-1,3506-25-0) → lysine methyl ester dihydrochloride (13515-95-2,15445-34-8,26348-70-9,34015-48-0,67396-08-1,130336-19-5)

Guidance literature:

methanol; With thionyl chloride; at 0 ℃; for 0.166667h;

L-lysine; at 0 ℃; for 3.16667h; Reflux;

DOI:10.1016/j.tet.2016.04.084

Reference yield: 99.4%

chloro-trimethyl-silane (75-77-4) + L-Lysine hydrochloride (657-27-2,10098-89-2,26124-78-7) → lysine methyl ester dihydrochloride (13515-95-2,15445-34-8,26348-70-9,34015-48-0,67396-08-1,130336-19-5)

Guidance literature:

In methanol;

upstream raw materials:

methanol

L-lysine

L-Lysine hydrochloride

2,2-dimethoxy-propane

Downstream raw materials:

N,O-bis(3,4-dimethoxycarbonylcaffeoyl)-L-lysine methyl ester

N^α-benzyloxycarbonyl-N^ε-(3-methyl-2-butenyl)oxycarbonyl-L-lysine methyl ester

N^α-(benzyloxycarbonyl)-N^ε-(tert-butoxycarbonyl)-L-lysine methyl ester

(S)-methyl 6-amino-2-(benzyloxycarbonylamino)hexanoate

Refernces

• 1、 Pandya, Anjali,Patravale, Vandana,Pukale, Sudeep. "Synthesis, characterization and topical application of novel bifunctional peptide metallodendrimer". . . Retrieved 2021/10/30.
• 2、 Yan, Jijun,Kang, Chuanqing,Bian, Zheng,Jin, Rizhe,Ma, Xiaoye,Gao, Lianxun. "Supramolecular self-assembly of chiral polyimides driven by repeat units and end groups". supporting information. p. 14723 - 14729. Retrieved 2017/11/28.