102611-15-4

Basic information

• Product Name: DECANOIC-10,10,10-D3 ACID
• Synonyms: DECANOIC ACID (METHYL-D3);DECANOIC-10,10,10-D3 ACID;Capric acid-10,10,10-d3;Decanoic-d3 Acid;CAPRIC ACID METHYL-D3
• CAS NO: 102611-15-4
• Molecular Formula: C10H17D3O2
• Molecular Weight: 175.28
• Mol File: 102611-15-4.mol
• Article Data: 0

Chemical Properties

• Melting Point: 30-32 °C(lit.)
• Boiling Point: 268-270 °C(lit.)
• Flash Point: 121.777 °C
• Appearance: /
• Density: 0.908 g/mL at 25 °C
• Storage Temp.: Room Temperature
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: DECANOIC-10,10,10-D3 ACID(CAS DataBase Reference)
• NIST Chemistry Reference: DECANOIC-10,10,10-D3 ACID(102611-15-4)
• EPA Substance Registry System: DECANOIC-10,10,10-D3 ACID(102611-15-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 102611-15-4(Hazardous Substances Data)

Usage

Description

Decanoic-10,10,10-D3 Acid is an isotope-labeled analog of Decanoic Acid, a medium-chain saturated fatty acid. It is characterized by its non-competitive antagonism at AMPA receptors, selectively reducing glutamate-induced currents in Xenopus oocytes expressing specific AMPA receptor subunits. DECANOIC-10,10,10-D3 ACID also exhibits inhibitory effects on epileptiform activity and demonstrates analgesic activity in rats. Additionally, it has been observed that plasma levels of decanoic acid are increased in patients with colorectal cancer.

Uses

Used in Pharmaceutical and Biomedical Research:
Decanoic-10,10,10-D3 Acid is used as an internal standard for the quantification of decanoic acid by GCor LC-MS. This application is crucial for accurate measurement and analysis of decanoic acid levels in various biological samples, aiding in research related to its potential therapeutic effects and role in disease states.
Used in Flavor and Fragrance Industry:
As an analog of decanoic acid, Decanoic-10,10,10-D3 Acid can be used in the manufacturing of esters for artificial fruit flavors and perfumes. This allows for the creation of unique and complex scents and tastes in various consumer products.
Used in Neuroscience Research:
Decanoic acid-d3 is utilized in studies investigating the role of AMPA receptors in neurological processes, such as epilepsy and cognitive function. Its ability to selectively modulate AMPA receptor activity makes it a valuable tool in understanding the underlying mechanisms of these conditions.
Used in Cancer Research:
The increased plasma levels of decanoic acid in patients with colorectal cancer suggest a potential role for this compound in cancer research. Decanoic-10,10,10-D3 Acid can be used as a tracer to study the relationship between decanoic acid and cancer progression, as well as to explore its potential as a biomarker or therapeutic agent in oncology.