11032-41-0 Usage
Description
DIHYDROERGOTAMINE MESYLATE is a semi-synthetic ergot alkaloid derivative that acts as a cerebral vasodilator and nootropic agent. It is known for its ability to improve blood flow in the brain and enhance cognitive function.
Uses
Used in Pharmaceutical Industry:
DIHYDROERGOTAMINE MESYLATE is used as a cognition adjuvant for improving cognitive function and memory in elderly patients with cognitive decline or vascular dementia. It is also used to treat symptoms of acute vascular events, such as transient ischemic attacks or stroke.
Brand names of DIHYDROERGOTAMINE MESYLATE include Alkergot (Sandoz), Circanol (3M Pharmaceuticals), Deapril (Bristol-Myers Squibb), Gerimal (Watson), and Hydergine (Novartis).
Originator
Redergin,Lek
Manufacturing Process
Dihydrotoxine is a mixture of three hydrogenated alkaloides of ergot spur.
(Claviceps purpurea). 10 g ergotoxine (the mixture of ergocornine,
ergocristine, ergocryptine 1:1:1) in 200 ml dioxane and 20 g Pd/BaSO4 were
stirred at a H2 pressure 10 atmospheres at 80°C for 5 hours. The catalyst was
filtered off, a filtrate was distilled to dryness in vacuum. The residue was in
chloroform dissolved and shook with aluminum oxide. The Al2O3 was filtered
off, the filtrate was crystallized after adding of hot benzene and cooling. Yield
6-8 g dihydroergotoxine. It crystallized with 1 mol of benzene. MP: 185°C.
Therapeutic Function
Vasodilator
Check Digit Verification of cas no
The CAS Registry Mumber 11032-41-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,1,0,3 and 2 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 11032-41:
(7*1)+(6*1)+(5*0)+(4*3)+(3*2)+(2*4)+(1*1)=40
40 % 10 = 0
So 11032-41-0 is a valid CAS Registry Number.