11103-57-4 Usage
Chemical Description
Vitamin A is a yellow, viscous compound with a boiling point of 125-135°C.
Description
Vitamin A, also known as retinol, is a fat-soluble vitamin that belongs to the retinoid class of compounds. It is composed of four isoprenoid units joined in a head-to-tail manner, with all double bonds in the E (trans) configuration. Vitamin A is essential for various bodily functions, including vision, immune function, and cell growth. It is found in various animal and plant sources, with provitamin A carotenoids being obtained from plant sources such as deep green, yellow, and orange fruits and vegetables.
Uses
Used in Skin Care Industry:
Vitamin A is used as a keratinization regulator for improving skin texture, firmness, and smoothness. It helps in the generation and function of skin cells, and its deficiency can lead to degeneration of dermal tissue, resulting in thick and dry skin. Topical application of vitamin A helps prevent skin dryness and scaliness, keeping the skin healthy, clear, and infection resistant. Its skin regeneration properties are enhanced when combined with vitamin E.
Used in Pharmaceutical Industry:
Vitamin A, in the form of retinol and its derivatives like retinol acetate, retinol propionate, and retinol palmitate, is used in the development of pharmaceutical products. These compounds have various applications, including the treatment of acne, skin aging, and other skin-related conditions.
Used in Food Industry:
Vitamin A is a major constituent of oils such as cod liver and shark, as well as many fish and vegetable oils. It is often added to food products to ensure adequate intake and maintain overall health.
History
The structure of vitamin A and some of the important derivatives are shown in Figure 1. The parent structure is all-trans-retinol [CAS: 68-26-8] and its IUPAC name is (all-E)-3,7-dimethyl-9-(2,6,6- trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol. The numbering system for vitamin A derivatives parallels the system used for the carotenoids. In older literature, vitamin A compounds are named as derivatives of trimethyl cyclohexene and the side chain is named as a substituent. For retinoic acid derivatives, the carboxyl group is denoted as C-1 and the trimethyl cyclohexane ring as a substituent on C-9. The structures of vitamin A and β-carotene were elucidated by Karrer in 1930 and several derivatives of the vitamin were prepared by this group. In 1935, Wald isolated a substance found in the visual pigments of the eye and was able to show that this material was identical with Karrer’s retinaldehyde.
Air & Water Reactions
Practically water insoluble.
Reactivity Profile
Vitamin A is light sensitive. Also air sensitive and heat sensitive. Reacts with strong oxidizing agents. Also can react with acids . Can react exothermically with reducing agents to release hydrogen gas.
Fire Hazard
Flash point data for Vitamin A are not available. Vitamin A is probably combustible.
Clinical Use
Vitamin A is used in the treatment of known or suspected vitamin A deficiency. Of course, vaccination is of prime importance; however, in underdeveloped countries where the rate of vaccination is low, vitamin A supplementation is a beneficial alternative.Retinoate analogs have been developed for use in the treatment of dermatological conditions such as psoriasis and acne.
Check Digit Verification of cas no
The CAS Registry Mumber 11103-57-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,1,1,0 and 3 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 11103-57:
(7*1)+(6*1)+(5*1)+(4*0)+(3*3)+(2*5)+(1*7)=44
44 % 10 = 4
So 11103-57-4 is a valid CAS Registry Number.
InChI:InChI=1/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6u,12-11+,16-8+,17-13u
