1157455-13-4 Usage
Description
1-(5-bromo-2-methyl-phenyl)-2,5-dimethyl-pyrrole is a chemical compound characterized by a molecular formula C12H13BrN. It is a pyrrole derivative featuring a bromine-substituted phenyl group and two methyl groups attached to the pyrrole ring. 1-(5-bromo-2-methyl-phenyl)-2,5-dimethyl-pyrrole holds potential applications in organic chemistry, materials science, and pharmaceuticals due to its unique structural features.
Uses
Used in Organic Chemistry:
1-(5-bromo-2-methyl-phenyl)-2,5-dimethyl-pyrrole is used as a building block for the synthesis of more complex organic molecules. Its unique structure allows for further chemical modifications and the creation of a diverse range of compounds with various properties and potential applications.
Used in Materials Science:
In the field of materials science, 1-(5-bromo-2-methyl-phenyl)-2,5-dimethyl-pyrrole is used for the development of new materials with specific electronic or optical properties. Its bromine-substituted phenyl group and methyl groups on the pyrrole ring contribute to the compound's potential in designing materials with tailored characteristics for specific applications.
Used in Pharmaceutical Industry:
1-(5-bromo-2-methyl-phenyl)-2,5-dimethyl-pyrrole is used as a potential candidate for the development of pharmaceutical drugs. Its structural features make it a promising compound for conditions where pyrrole-containing molecules have demonstrated biological activity. Further research is necessary to explore its full potential in drug development and to understand its properties and uses in this context.
Further research and investigation are required to fully comprehend and exploit the potential uses and properties of 1-(5-bromo-2-methyl-phenyl)-2,5-dimethyl-pyrrole across these industries.
Check Digit Verification of cas no
The CAS Registry Mumber 1157455-13-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,5,7,4,5 and 5 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1157455-13:
(9*1)+(8*1)+(7*5)+(6*7)+(5*4)+(4*5)+(3*5)+(2*1)+(1*3)=154
154 % 10 = 4
So 1157455-13-4 is a valid CAS Registry Number.
1157455-13-4Relevant articles and documents
Novel Series of Dihydropyridinone P2X7 Receptor Antagonists
Lopez-Tapia, Francisco,Walker, Keith A. M.,Brotherton-Pleiss, Christine,Caroon, Joanie,Nitzan, Dov,Lowrie, Lee,Gleason, Shelley,Zhao, Shu-Hai,Berger, Jacob,Cockayne, Debra,Phippard, Deborah,Suttmann, Rebecca,Fitch, William L.,Bourdet, David,Rege, Pankaj,Huang, Xiaojun,Broadbent, Scott,Dvorak, Charles,Zhu, Jiang,Wagner, Paul,Padilla, Fernando,Loe, Brad,Jahangir, Alam,Alker, André
supporting information, p. 8413 - 8426 (2015/11/24)
Identification of singleton P2X7 inhibitor 1 from HTS gave a pharmacophore that eventually turned into potential clinical candidates 17 and 19. During development, a number of issues were successfully addressed, such as metabolic stability, plasma stability, GSH adduct formation, and aniline mutagenicity. Thus, careful modification of the molecule, such as conversion of the 1,4-dihydropyridinone to the 1,2-dihydropyridinone system, proper substitution at C-5″, and in some cases addition of fluorine atoms to the aniline ring allowed for the identification of a novel class of potent P2X7 inhibitors suitable for evaluating the role of P2X7 in inflammatory, immune, neurologic, or musculoskeletal disorders.
