120743-99-9

Basic information

• Product Name: 4-((TERT-BUTYLDIMETHYLSILYL)OXY)BENZALD&
• Synonyms: 4-((TERT-BUTYLDIMETHYLSILYL)OXY)BENZALD&;4-(tert-Butyldimethylsiloxy)benzaldehyde;4-(t-ButyldiMethylsilyloxy)benzaldehyde;4-[(tert-Butyldimethylsilyl)oxy]benzaldehyde 97%
• CAS NO: 120743-99-9
• Molecular Formula: C₁₃H₂₀O₂Si
• Molecular Weight: 236.38
• Product Categories: Aldehydes;C10 to C21;Carbonyl Compounds
• Mol File: 120743-99-9.mol
• Article Data: 147

Chemical Properties

• Boiling Point: 224-226 °C(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 0.957 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.00467mmHg at 25°C
• Refractive Index: n20/D 1.5110(lit.)
• CAS DataBase Reference: 4-((TERT-BUTYLDIMETHYLSILYL)OXY)BENZALD&(CAS DataBase Reference)
• NIST Chemistry Reference: 4-((TERT-BUTYLDIMETHYLSILYL)OXY)BENZALD&(120743-99-9)
• EPA Substance Registry System: 4-((TERT-BUTYLDIMETHYLSILYL)OXY)BENZALD&(120743-99-9)

Safety Data

• Hazard Codes: Xi
• Statements: 41
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 120743-99-9(Hazardous Substances Data)

Usage

Description

4-((TERT-BUTYLDIMETHYLSILYL)OXY)BENZALD&, also known as 4-(tert-butyldimethylsilyloxy)benzaldehyde, is an organic compound that serves as a versatile reagent in the synthesis of various organic compounds. It is characterized by the presence of a tert-butyldimethylsilyl ether group, which provides unique properties and reactivity to the molecule.

Uses

Used in Pharmaceutical Industry:
4-((TERT-BUTYLDIMETHYLSILYL)OXY)BENZALD& is used as a reagent for the synthesis of benzimidazoles, which are important structural motifs in the development of pharmaceutical compounds. Benzimidazoles exhibit a wide range of biological properties, making them valuable in the creation of drugs for various therapeutic applications.
Used in Chemical Research:
In the field of chemical research, 4-((TERT-BUTYLDIMETHYLSILYL)OXY)BENZALD& is utilized as a reagent for the synthesis of various organic compounds. Its unique reactivity and the presence of the tert-butyldimethylsilyl ether group make it a valuable tool for exploring new chemical reactions and developing novel synthetic pathways.
Used in Material Science:
4-((TERT-BUTYLDIMETHYLSILYL)OXY)BENZALD& can also be employed in material science for the development of new materials with specific properties. The synthesis of benzimidazoles and other organic compounds using this reagent can lead to the creation of advanced materials with applications in various industries, such as electronics, coatings, and textiles.

InChI:InChI=1/C13H20O2Si/c1-13(2,3)16(4,5)15-12-8-6-11(10-14)7-9-12/h6-10H,1-5H3

Upstream product

• 117635-46-8 1-(tert-butyldimethylsilyloxy)-4-((tert-butyldimethylsilyloxy)methyl)benzene 
• 438457-58-0 (4-{[tert-butyl(dimethyl)silyl]oxy}phenyl)methylene diacetate 
• 41879-37-2 t-butyldimethylsilyl amine 
• 123-08-0 4-hydroxy-benzaldehyde 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 623-27-8 terephthalaldehyde, 
• 6399-81-1 triphenylphosphine hydrobromide 
• 100-51-6 benzyl alcohol 
• 351-70-2 benzyl trifluoroacetate 
• 156878-45-4 4-<(tert-Butyldimethylsilyl)oxy>benzyl trifluoroacetate 
• 7087-68-5 N-ethyl-N,N-diisopropylamine 
• 288-32-4 1H-imidazole 
• 836-42-0 4-benzyloxybenzyl chloride 

Downstream Products

• 380915-08-2 1-[4-(tert-butyldimethylsilanyloxy)phenyl]-3-trimethylsilanylprop-2-yn-1-ol 
• 438457-58-0 (4-{[tert-butyl(dimethyl)silyl]oxy}phenyl)methylene diacetate 
• 566899-06-7 4-(tert-butyldimethylsilyloxy)-α-(3'-methoxyphenyl)benzyl alcohol 
• 244293-43-4 ethyl (E)-3-(4-(((tert-butyldimethylsilyl)oxy)phenyl)acrylate) 
• 849813-42-9 7-(tert-butyldimethylsilanyloxy)-1-(4-hydroxyphenyl)hept-1-en-3-one 
• 849813-41-8 7-(tert-butyldimethylsilanyloxy)-1-[4-(tertbutyldimethylsilanyloxy)phenyl]hept-1-en-3-one 
• 515869-57-5 1-[4'-(tert-butyldimethylsilyloxy)phenyl]prop-2-yn-1-ol 
• 459867-19-7 N-{2-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-2-hydroxy-ethyl}-2-(3,4-dimethoxy-phenyl)-acetamide 
• 444806-78-4 1-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-2-[2-(3,4-dimethoxy-phenyl)-ethylamino]-ethanol 
• 444806-77-3 2-amino-1-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-ethanol 
• 71771-90-9 denopamine 
• 521274-34-0 phenoxy-acetic acid 1-[2-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-5-[2-(3-ethyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)-vinyl]-5-(2-trityloxy-ethyl)-[1,3]dioxolan-4-ylmethyl]-5-[3-(4-methoxy-phenoxymethoxy)-cyclohexyl]-penta-2,4-dienyl ester 
• 521274-35-1 phenoxy-acetic acid 1-{5-(2-allyloxycarbonylamino-ethyl)-2-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-5-[2-(3-ethyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)-vinyl]-[1,3]dioxolan-4-ylmethyl}-5-[3-(4-methoxy-phenoxymethoxy)-cyclohexyl]-penta-2,4-dienyl ester 
• 521274-32-8 (5S,6S)-6-((E)-2-{(2R,4R,5R)-2-(4-{[tert-butyl(dimethyl)silyl]oxy}phenyl)-5-((2R,5Z)-2-hydroxy-6-{(1R,3S)-3-[(4-methoxyphenoxy)methoxy]cyclohexyl}hex-5-en-3-ynyl)-4-[2-(trityloxy)ethyl]-[1,3]dioxolan-4-yl}vinyl)-5-ethyl-5,6-dihydro-2H-pyran-2-one 

Relevant articles and documents

Dearomatizing spirocyclization of thioureas, ureas and guanidines

An investigation of the dearomatization reactions of benzylic thioureas, ureas and guanidines using hypervalent iodine reagents is described. Initial attempts to perform this reaction with methyl aryl ethers was compromised by electrophilic addition leadi

Catalytic synthesis of aldehydes and ketones under mild conditions using tempo/oxone

A novel, metal-free oxidation system for the catalytic synthesis of aldehydes and ketones - TEMPO/Oxone - has been developed. An optimized reaction protocol proved especially successful for the synthesis of ketones. Additionally, the influence of quarternary ammonium salts on the catalysis was studied. The mild conditions of this novel procedure were shown to tolerate even sensitive silyl protective groups which can otherwise be cleaved in the presence of Oxone.

Synthesis of amphiphilic diblock copolymers of isotactic polystyrene-block-isotactic poly(p-hydroxystyrene) using a titanium complex with an [OSSO]-type bis(phenolate) ligand and sequential monomer addition

A series of isotactic diblock copolymers of polystyrene-block-poly(p-tert-butyldimethylsilyloxystyrene) (iPS-b-iP(p-TBDMSOS)) were successfully synthesized using living coordination polymerization techniques with a kind of titanium dichloro complex contai

Metallocene-mediated synthesis of chain-end functionalized polypropylene and application in PP/clay nanocomposites

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