121662-14-4 Usage
Description
(+/-)-IBUPROFEN-D3 is a deuterated analogue of Ibuprofen, a widely used nonsteroidal anti-inflammatory drug (NSAID). It is a selective cyclooxygenase inhibitor with an IC50 value of 14.9 μM, inhibiting both PGH synthase-1 and PGH synthase-2 with comparable potency. As a Colourless Crystalline Solid, (+/-)-IBUPROFEN-D3 is commonly used as an internal standard in various applications.
Uses
Used in Pharmaceutical Industry:
(+/-)-IBUPROFEN-D3 is used as an internal standard for the quantification of Ibuprofen by GCor LC-mass spectrometry. This application is crucial for ensuring accurate measurements and analysis of Ibuprofen levels in pharmaceutical formulations, research studies, and quality control processes.
Used in Research Applications:
As a selective cyclooxygenase inhibitor, (+/-)-IBUPROFEN-D3 is used in research to study the inhibition of PGH synthase-1 and PGH synthase-2 enzymes, which play a significant role in the synthesis of prostaglandins. This helps researchers understand the mechanism of action of Ibuprofen and its potential applications in treating inflammation and pain.
Used in Quality Control:
(+/-)-IBUPROFEN-D3 serves as an essential tool in quality control processes for pharmaceutical companies. By using it as an internal standard, laboratories can accurately determine the concentration of Ibuprofen in various products, ensuring their safety, efficacy, and compliance with regulatory standards.
Check Digit Verification of cas no
The CAS Registry Mumber 121662-14-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,1,6,6 and 2 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 121662-14:
(8*1)+(7*2)+(6*1)+(5*6)+(4*6)+(3*2)+(2*1)+(1*4)=94
94 % 10 = 4
So 121662-14-4 is a valid CAS Registry Number.
InChI:InChI=1/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)/i3D3
