13241-33-3

Basic information

• Product Name: Neohesperidin
• Synonyms: Neohesperidin HPLC 96% Min;Neohesperidin≥ 98% (HPLC);(s)-a-d-glucopyranosyl)oxy)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl);4h-1-benzopyran-4-one,2,3-dihydro-7-((2-o-(6-deoxy-alpha-l-mannopyranosyl)-bet;HESPERETIN-7-NEOHESPERIDOSIDE;HESPERETIN-7-O-NEOHESPERIDOSIDE;(S)-7-(((2-O-6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one;(S)-4'-METHOXY-3',5,7-TRIHYDROXYFLAVONE-7-[2-O-(ALPHA-L-RHAMNOPYRANOSYL)-BETA-D-GLUCOPYRANOSIDE]
• CAS NO: 13241-33-3
• Molecular Formula: C₂₈H₃₄O₁₅
• Molecular Weight: 610.56
• EINECS: 236-216-9
• Product Categories: Inhibitors;Flavanones;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 13241-33-3.mol
• Article Data: 0

Chemical Properties

• Melting Point: 239-243°C
• Boiling Point: 933.7 ºC at 760 mmHg
• Flash Point: 306.7 ºC
• Appearance: /
• Density: 1.65 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.695
• Storage Temp.: 2-8°C
• Solubility: DMSO (Slightly), Pyridine (Slightly)
• PKA: 7.14±0.40(Predicted)
• Water Solubility: 3.98mg/L at 20℃
• BRN: 74945
• CAS DataBase Reference: Neohesperidin(CAS DataBase Reference)
• NIST Chemistry Reference: Neohesperidin(13241-33-3)
• EPA Substance Registry System: Neohesperidin(13241-33-3)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• RTECS: DJ2981400
• F: 10-21
• Hazardous Substances Data: 13241-33-3(Hazardous Substances Data)

Usage

Description

Neohesperidin is a flavonoid found in citrus fruit peel that possesses diverse biological activities, including antioxidant, hypolipidemic, and bone-protective properties. It is a white powder and a flavanone glycoside that is hesperitin with a 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety attached to the 7-hydroxy group.

Uses

Used in Cosmetic Products:
Neohesperidin is used as an ingredient in cosmetic products for its antioxidant and skin health benefits.
Used in Food & Beverages:
Neohesperidin is used as a sweetening agent in food and beverages due to its natural sweetness and low-calorie properties.
Used in Antioxidant Applications:
Neohesperidin is used as an antioxidant flavanone glycoside for its ability to protect cells from oxidative damage and support overall health.
Used in Lipid Regulation:
Neohesperidin exhibits lipid-regulating effects in vivo and in vitro, making it useful in managing lipid levels and promoting cardiovascular health.
Used in Bone Health:
Neohesperidin administration protects ovariectomized mice from bone loss, indicating its potential use in maintaining bone health and preventing bone-related disorders.
Used in Diabetes Management:
In a mouse model of diabetes, neohesperidin increases glucose tolerance, decreases insulin resistance, and reduces serum triglycerides and total cholesterol, suggesting its potential use in managing diabetes and related metabolic disorders.

Flammability and Explosibility

Notclassified

InChI:InChI=1/C28H34O15/c1-10-21(33)23(35)25(37)27(39-10)43-26-24(36)22(34)19(9-29)42-28(26)40-12-6-14(31)20-15(32)8-17(41-18(20)7-12)11-3-4-16(38-2)13(30)5-11/h3-7,10,17,19,21-31,33-37H,8-9H2,1-2H3/t10-,17-,19+,21-,22+,23+,24-,25+,26+,27-,28+/m0/s1

Downstream Products

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