14091-15-7

Basic information

• Product Name: 4-BROMO-DL-PHENYLALANINE
• Synonyms: 4-BROMO-DL-PHENYLALANINE;4-BROMO-PHENYLALANINE;2-AMINO-3-(4-BROMO-PHENYL)-PROPIONIC ACID;DL-P-BROMOPHENYLALANINE;H-P-BROMO-DL-PHE-OH;H-DL-PHE(4-BR)-OH;H-DL-PHE(P-BR)-OH;P-BROMO-DL-PHENYLALANINE
• CAS NO: 14091-15-7
• Molecular Formula: C₉H₁₀BrNO₂
• Molecular Weight: 244.09
• EINECS: 237-941-3
• Product Categories: Peptide Synthesis;Phenylalanine Derivatives;Unnatural Amino Acid Derivatives
• Mol File: 14091-15-7.mol
• Article Data: 6

Chemical Properties

• Melting Point: 262-263 °C (dec.)(lit.)
• Boiling Point: 368.406 °C at 760 mmHg
• Flash Point: 176.606 °C
• Appearance: White/Powder
• Density: 1.5757 (rough estimate)
• Vapor Pressure: 4.46E-06mmHg at 25°C
• Refractive Index: 1.6120 (estimate)
• Storage Temp.: 0-6°C
• PKA: 2.18±0.10(Predicted)
• BRN: 2212158
• CAS DataBase Reference: 4-BROMO-DL-PHENYLALANINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-DL-PHENYLALANINE(14091-15-7)
• EPA Substance Registry System: 4-BROMO-DL-PHENYLALANINE(14091-15-7)

Safety Data

• Safety Statements: 24/25-22
• WGK Germany: 3
• Hazardous Substances Data: 14091-15-7(Hazardous Substances Data)

Usage

Chemical Properties

white powder

InChI:InChI=1/C9H10BrNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)/t8-/m1/s1

Upstream product

• 7647-01-0 hydrogenchloride 
• 71078-92-7 diethyl (acetylamino)<(4-bromophenyl)methyl>propanedioate 
• 589-15-1 1-bromomethyl-4-bromobenzene 
• 1200-07-3 3-(4-bromophenyl)acrylic acid 
• 1353886-56-2 ethyl 3-(4-bromophenyl)-2-(hydroxyimino)propionate 
• 204506-95-6 methyl (N-benzoyl)-4'-bromophenylalaninate 
• 469898-10-0 (Z)-2-phenyl-4-(4-bromobenzylidene)-(4H)-1,3-oxazol-5-one 
• 7664-41-7 ammonia 
• 92013-18-8 2-[(4-bromophenyl)methyl]propanedioic acid 

Downstream Products

• 166967-59-5 ethyl 2-amino-3-(4-bromophenyl) propanoate 
• 171095-12-8 N-acetyl-4-bromophenylalanine 
• 73918-56-6 4-Bromophenethylamine 

Relevant articles and documents

Organocatalytic Enantioselective Addition of α-Aminoalkyl Radicals to Isoquinolines

With a dual organocatalytic system involving a chiral phosphoric acid and a dicyanopyrazine-derived chromophore (DPZ) photosensitizer and under the irradiation with visible light, an enantioselective Minisci-type addition of α-amino acid-derived redox-active esters (RAEs) to isoquinolines has been developed. A variety of prochiral α-aminoalkyl radicals generated from RAEs were successfully introduced on isoquinolines, providing a range of valuable α-isoquinoline-substituted chiral secondary amines in high yields with good to excellent enantioselectivities.

Enhanced reduction of C-N multiple bonds using sodium borohydride and an amorphous nickel catalyst

Amorphous nickel powder (Ni0) was utilised as a catalyst under mild, aqueous, basic conditions for enhancing the sodium borohydride-mediated reduction of C-N multiple bonds such as oximes, imines, hydrazones and nitriles to produce the corresponding amines in good to excellent yields.