1416209-39-6

Basic information

• Product Name: 4-methyl-2-({[3-methyl-2,6-dioxo-7-(2-oxo-2-phenylethyl)-2,3,6,7-tetrahydro-1H-purin-8-yl]methyl}thio)-5,6,7,8-tetrahydroquinoline-3-carbonitrile
• CAS NO: 1416209-39-6
• Molecular Weight: 500.581
• Mol File: 1416209-39-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-methyl-2-({[3-methyl-2,6-dioxo-7-(2-oxo-2-phenylethyl)-2,3,6,7-tetrahydro-1H-purin-8-yl]methyl}thio)-5,6,7,8-tetrahydroquinoline-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-2-({[3-methyl-2,6-dioxo-7-(2-oxo-2-phenylethyl)-2,3,6,7-tetrahydro-1H-purin-8-yl]methyl}thio)-5,6,7,8-tetrahydroquinoline-3-carbonitrile(1416209-39-6)
• EPA Substance Registry System: 4-methyl-2-({[3-methyl-2,6-dioxo-7-(2-oxo-2-phenylethyl)-2,3,6,7-tetrahydro-1H-purin-8-yl]methyl}thio)-5,6,7,8-tetrahydroquinoline-3-carbonitrile(1416209-39-6)

Safety Data

• Hazardous Substances Data: 1416209-39-6(Hazardous Substances Data)

Upstream product

• 1170005-16-9 C₁₅H₁₃ClN₄O₃ 
• 95546-96-6 1-methyl-3-thioxo-2,3,5,6,7,8-hexa-hydroisoquinoline-4-carbonitrile 

Downstream Products

• 1416209-48-7 2,14-dimethyl-8-phenyl-3,4,5,6-tetrahydro-9H-purino[7'',8'':1',7'][1,4]diazepino[5',6':4,5]thieno-[2,3-c]isoquinoline-11,13(12H,14H)-dione 
• 1416209-49-8 1,9-dimethyl-7-phenyl-10,11,12,13-tetrahydro-1H-purino[7,8:1',7'][1,4]diazepino[5',6':4,5]thieno[2,3-b]quinoline-2,4(3H,6H)-dione 

Relevant articles and documents

Condensed sulfur-containing pyridine systems 3.*Construction of penta- and hexacyclic heterocyclic systems by the cascade reaction of 3-cyanopyridine-2(1H)-thiones and 3-cyano-pyridine-2(1H)-thiolates with 8-chloromethyl-3-methyl-7-(2-oxo-2-phenylethyl)xanthene

The alkylation of 3-cyanopyridine-2(1H)-thiones with 8-chloromethyl-3- methyl-7-(2-oxo-2-phenylethyl)- xanthene in a KOH-H2O-DMF system upon heating leads to the formation of pyrido-[3″,2″:4′,5′] thieno[3′,2′:5,6][1,4]diazepino[7,1-f]purine-2,4(3H,6H)-dione derivatives in good yields. Under milder conditions, the intermediates of the cascade reactions, namely, 2-({[3-methyl-2,6-dioxo-7-(2-oxo-2-phenylethyl)-2,3, 6,7-tetrahydro-1H-purin-8-yl]methyl}thio)pyridine-3-carbonitriles, can be isolated and characterized.