14485-07-5

Basic information

• Product Name: carboxyl radical
• Synonyms: carboxyl radical;Carbon dioxide ion;Carbon dioxide, ion(1-);oxidooxomethyl
• CAS NO: 14485-07-5
• Molecular Formula: CO₂
• Molecular Weight: 0
• Mol File: 14485-07-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 0.984g/cm³
• CAS DataBase Reference: carboxyl radical(CAS DataBase Reference)
• NIST Chemistry Reference: carboxyl radical(14485-07-5)
• EPA Substance Registry System: carboxyl radical(14485-07-5)

Safety Data

• Hazardous Substances Data: 14485-07-5(Hazardous Substances Data)

Usage

Description

The carboxyl radical is an organic radical anion derived from carbon dioxide, characterized by its metabolite nature of carbon tetrachloride. It possesses a functional group consisting of a carbon atom double-bonded to an oxygen atom and single-bonded to a hydroxyl group, represented as -COOH. This functional group is essential in various biochemical reactions and plays a significant role in the structure and properties of organic compounds.

Uses

1. Used in Pharmaceutical Applications:
The carboxyl radical is used as a key functional group in the development of pharmaceutical compounds for various therapeutic applications. Its ability to form hydrogen bonds and coordinate with metal ions allows for the creation of molecules with specific biological activities and improved pharmacokinetic properties.
2. Used in Drug Delivery Systems:
In the field of drug delivery, the carboxyl radical is utilized as a targeting moiety for the development of targeted drug delivery systems. Its ability to form stable complexes with various biomolecules enables the selective delivery of therapeutic agents to specific cells or tissues, thereby enhancing the efficacy and reducing the side effects of the treatment.
3. Used in Chemical Synthesis:
The carboxyl radical is employed as a versatile building block in organic synthesis, allowing for the creation of a wide range of organic compounds with diverse structures and properties. Its reactivity and ability to participate in various chemical reactions, such as esterification, amidation, and carboxylation, make it a valuable tool in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
4. Used in Material Science:
In material science, the carboxyl radical is used as a functional group to modify the properties of polymers and other materials. Its ability to form strong interactions with other molecules and surfaces can be exploited to improve the mechanical, thermal, and chemical properties of materials, as well as to introduce specific functionalities, such as biocompatibility, responsiveness, or self-assembly capabilities.
5. Used in Environmental Applications:
The carboxyl radical is also utilized in environmental applications, such as the removal of pollutants from water and air. Its ability to form complexes with metal ions and other contaminants allows for the development of efficient adsorbents and filters for the purification of contaminated media.

InChI:InChI=1/CHO2/c2-1-3/h(H,2,3)/p-1

Upstream product

• 124-38-9 carbon dioxide 
• 71-47-6 formate 
• 15784-30-2 2-amino-2-carboxy-1,1-dimethyl-ethylsulfanyl 
• 68570-60-5 2-hydroxy-ethylsulfanyl 

Downstream Products

• 47780-35-8 Co(2,2'-bipyridinyl)3⁽¹⁺⁾ 
• 124-38-9 carbon dioxide 
• 23852-07-5 {Co dpy2}⁽¹⁺⁾ 
• 47837-97-8 {Co(4,4'-dimethyl-2,2'-bipyridine)3}⁽¹⁺⁾ 
• 65881-93-8 phenyl t-butyl nitrone-formate adduct 

Relevant articles and documents

Voltammetric Study on CO2 Reduction Electrocatalyzed by Cobalt Tetraphenylporphine in DMF Solution

The homogenous catalysis of cobalt tetraphenylporphine (CoTPP) in the electroreduction of CO2 was investigated by means of cyclic voltammetry (CV).Based on the kinetical treatment of the data, the rate constant for the electron transfer to CO2 from CoTPP dianion could be determined and the activation energy of the step was estimated as 34.5 kJ/mol.