16937-03-4

Basic information

• Product Name: Benzenesulfonamide, N-(4-chlorophenyl)-4-nitro-
• Synonyms: N-(4-chlorophenyl)-4-nitrobenzenesulfonamide
• CAS NO: 16937-03-4
• Molecular Formula: C₁₂H₉ClN₂O₄S
• Molecular Weight: 312.72886
• Mol File: 16937-03-4.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzenesulfonamide, N-(4-chlorophenyl)-4-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, N-(4-chlorophenyl)-4-nitro-(16937-03-4)
• EPA Substance Registry System: Benzenesulfonamide, N-(4-chlorophenyl)-4-nitro-(16937-03-4)

Safety Data

• Hazardous Substances Data: 16937-03-4(Hazardous Substances Data)

Upstream product

• 71597-85-8 (p-hydroxyphenyl)boronic acid 
• 5720-07-0 4-methoxyphenylboronic acid 
• 5720-05-8 4-methylphenylboronic acid 
• 4612-26-4 1,4-Phenyldiboronic acid 
• 4612-28-6 1,3-phenylenediboronic acid 
• 13506-83-7 [2-(dihydroxyboranyl)phenyl]boronic acid 
• 1692-15-5 4-pyridylboronic acid 
• 1692-25-7 3-pyridylboronic acid 
• 1679-18-1 4-Chlorophenylboronic acid 
• 63503-60-6 3-chlorophenylboronic acid 
• 98-74-8 4-Nitrobenzenesulfonyl chloride 
• 62-53-3 aniline 
• 1576-44-9 N-nosylaniline 
• 73901-01-6 p-nitrobenzenesulfonyl azide 

Downstream Products

• 16803-92-2 4-amino-N-(4-chlorophenyl)benzenesulfonamide 
• 1383579-50-7 N-({4-amino-2-(methylthio)furo[2,3-d]pyrimidin-5-yl}methyl)-N-(4-chlorophenyl)-4-nitrobenzenesulfonamide 
• 1383579-60-9 5-[(4-chlorophenylamino)methyl]-2-(methylthio)furo[2,3-d]pyrimidin-4-amine 
• 69751-90-2 4'-chloro-N-methyl-4-nitrobenzenesulfonanilide 

Relevant articles and documents

An overview on the progress and development on the palladium catalyzed direct cyanation

Generation of the positive CN ion and the corresponding direct cyanation are both extremely important for cyanation of aromatic compounds. Hereby, we would like to report the simultaneous use of the new Pd nano-catalyst as well as the three types of the N-arylsulfonyl cyanamides (A, B and C) as potent reagents for the in situ generation of the positive CN ion for the direct cyanation of phenylboronic acids in acetonitrile at reflux conditions.

Flexibility of small molecular CD4 mimics as HIV entry inhibitors

CD4 mimics such as YIR-821 and its derivatives are small molecules which inhibit the interaction between the Phe43 cavity of HIV-1 gp120 with host CD4, an interaction that is involved in the entry of HIV to cells. Known CD4 mimics generally possess three

N-Acyl-N-(4-chlorophenyl)-4-nitrobenzenesulfonamides: Highly selective and efficient reagents for acylation of amines in water

A variety of N-acyl-N-(4-chlorophenyl)-4-nitrobenzenesulfonamides (1a-e) were synthesized in one pot from 4-chloroaniline under solvent-free conditions and have been developed as chemoselective N-acylation reagents. Selective protection of primary amines in the presence of secondary amines, acylation of aliphatic amines in the presence of aryl amines, and monofunctionalization of primary-secondary diamines as well as selective N-acylation of amino alcohols using these reagents are described. All of the acylation reactions were carried out in water as a green solvent. High stability and easy preparation of these acylating reagents are other advantages of this method.