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17354-63-1

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17354-63-1 Usage

Description

1-(P-METHOXYPHENYL)2-NITROPROPENE, also known as PM2NP, is an organic chemical compound that serves as a crucial intermediate in the synthesis of various pharmaceuticals. It is characterized by its molecular structure, which includes a p-methoxyphenyl group and a nitro group attached to a propene backbone. 1-(P-METHOXYPHENYL)2-NITROPROPENE plays a significant role in the development of designer drugs and has potential applications in the pharmaceutical industry.

Uses

1. Used in Pharmaceutical Synthesis:
1-(P-METHOXYPHENYL)2-NITROPROPENE is used as an intermediate in the synthesis of 4-Methoxyamphetamine Hydrochloride (M261015), which is a designer drug belonging to the amphetamine class. This designer drug is known for its ability to release 5-hydroxytryptamine (serotonin) in brain tissue, making it a subject of interest for researchers and pharmaceutical companies.
2. Used in the Amphetamine Industry:
In the amphetamine industry, 1-(P-METHOXYPHENYL)2-NITROPROPENE is used as a key component in the production of 4-Methoxyamphetamine Hydrochloride. 1-(P-METHOXYPHENYL)2-NITROPROPENE is valuable for its potential effects on the central nervous system, particularly its influence on serotonin levels. The development and study of such designer drugs can lead to a better understanding of the mechanisms underlying various neurological and psychiatric disorders, as well as the discovery of new therapeutic approaches.
3. Used in Research and Development:
1-(P-METHOXYPHENYL)2-NITROPROPENE is also utilized in research and development for its potential applications in the creation of new drugs and pharmaceuticals. Its unique molecular structure allows for further modification and exploration of its properties, which could lead to the discovery of novel compounds with specific therapeutic effects.

Check Digit Verification of cas no

The CAS Registry Mumber 17354-63-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,3,5 and 4 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 17354-63:
(7*1)+(6*7)+(5*3)+(4*5)+(3*4)+(2*6)+(1*3)=111
111 % 10 = 1
So 17354-63-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H11NO3/c1-8(11(12)13)7-9-3-5-10(14-2)6-4-9/h3-7H,1-2H3

17354-63-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(P-METHOXYPHENYL)2-NITROPROPENE

1.2 Other means of identification

Product number -
Other names Benzene,1-methoxy-4-(2-nitro-1-propenyl)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:17354-63-1 SDS

17354-63-1Relevant articles and documents

Reactions of 1-Aryl-1,2-dibromo-2-nitropropanes with 2-Nitro-2-propyl Anion in DMSO

Cho, Bong Rae,Suh, Young Sung,Lee, Seung Jae,Cho, Eun Jeong

, p. 3681 - 3682 (1994)

-

A diversity-oriented synthesis of polyheterocycles: Via the cyclocondensation of azomethine imine

Ansari, Arshad J.,Pathare, Ramdas S.,Kumawat, Anita,Maurya, Antim K.,Verma, Sarika,Agnihotri, Vijai K.,Joshi, Rahul,Metre, Ramesh K.,Sharon, Ashoke,Pardasani,Sawant, Devesh M.

supporting information, p. 13721 - 13724 (2019/09/16)

Pd-Catalyzed sequential reactions to afford skeletally diverse molecules are described. The reaction involved azomethine imine formation and a cyclocondensation reaction as individual steps. The methodology provides excellent regio- and stereocontrol. Skeletal diversity was ensured by changing the electrophilic counterpart of azomethine imine. Due to its broader diversity and complexity, the DOS methodology is likely to benefit drug discovery and development in the future.

METHODS AND COMPOSITIONS FOR SELECTIVE AND TARGETED CANCER THERAPY

-

Page/Page column 228, (2015/03/28)

Provided herein are methods and compositions for selective and targeted cancer therapy, in particular certain benzothiophenes, benzothiazoles, oxalamides, N-acyl ureas and chromones, and their use in selectively treating certain adenocarcinomas. In some embodiments, the selective toxicity of the compounds may be mediated through SCD1 and/or CYP450 such as CYP4F11.

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