19427-82-8 Usage
Description
Selindin, a phenanthroindolizidine alkaloid, is a plant-derived organic compound characterized by the presence of nitrogen atoms in its heterocyclic ring. It is predominantly found in species such as Delphinium, Aconitum, and Anisodus, and is recognized for its potent toxic and psychoactive effects on the central nervous system. As a sodium channel blocker, Selindin can cause muscle paralysis, cardiac arrhythmias, and neurotoxicity. Its high lipophilicity enables it to cross the blood-brain barrier easily, intensifying its impact on the central nervous system. Due to these toxic properties, Selindin is classified as a hazardous substance that requires careful handling.
Uses
Given the provided materials, there are no specific applications listed for Selindin. However, it is important to note that due to its toxic and psychoactive effects, Selindin is not typically used in commercial or medicinal applications. Instead, it is primarily recognized for its potential dangers and the need for caution in handling this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 19427-82-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,4,2 and 7 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 19427-82:
(7*1)+(6*9)+(5*4)+(4*2)+(3*7)+(2*8)+(1*2)=128
128 % 10 = 8
So 19427-82-8 is a valid CAS Registry Number.
InChI:InChI=1/C19H20O5/c1-5-11(2)18(21)22-15-10-13-14(24-19(15,3)4)8-6-12-7-9-16(20)23-17(12)13/h5-9,15H,10H2,1-4H3/b11-5-/t15-/m1/s1
19427-82-8Relevant articles and documents
The absolute configuration of angular 3′-acyloxypyranocoumarins by vibrational circular dichroism exciton chirality
Buenda-Trujillo, Abigail I.,Torrres-Valencia, J. Martn,Joseph-Nathan, Pedro,Burgueo-Tapia, Eleuterio
, p. 1418 - 1423 (2015/02/02)
A complex mixture of lomatin C-3′ esters and (-)-O-angeloyllomatin 1 was isolated from the seeds of Prionosciadium thapsoides. Since a literature search revealed that some lomatin C-3′ monoesters have positive specific rotations, while others had negative values, the absolute configuration of all of the molecules was determined to be (R) by exciton chirality in the infrared region, and by chemical correlation. A single crystal X-ray study of acetyllomatin 3, using the Flack and Hooft parameters, independently confirmed this absolute configuration.
