23100-12-1 Usage
Description
2-Chloropyridine-5-carbaldehyde is an off-white crystalline compound that serves as a valuable building block in the synthesis of various organic compounds, particularly in the pharmaceutical industry. Its unique chemical structure, featuring a chloro substituent at the 2nd position and a formyl group at the 5th position of the pyridine ring, endows it with versatile reactivity and functional group compatibility.
Uses
Used in Pharmaceutical Industry:
2-Chloropyridine-5-carbaldehyde is used as a pharmaceutical intermediate for the synthesis of a wide range of therapeutic agents. Its presence in the molecular structure of target compounds allows for the modulation of biological activity, enhancing the potency and selectivity of the resulting drugs.
As a Key Building Block:
2-Chloropyridine-5-carbaldehyde is utilized as a key building block in the development of novel pharmaceuticals, providing a convenient and efficient route to access complex heterocyclic scaffolds. Its reactivity allows for the formation of various functional groups and the construction of diverse molecular frameworks, which are essential for the discovery of new drugs with improved pharmacological properties.
In Medicinal Chemistry Research:
2-Chloropyridine-5-carbaldehyde is employed as a starting material in medicinal chemistry research, enabling the design and synthesis of innovative drug candidates. Its unique structural features and synthetic versatility make it an attractive choice for the development of new therapeutic agents with potential applications in various disease areas, including infectious diseases, cancer, and neurological disorders.
Overall, 2-Chloropyridine-5-carbaldehyde plays a crucial role in the pharmaceutical industry, acting as a versatile intermediate and building block for the synthesis of a diverse array of therapeutic agents. Its unique chemical properties and synthetic potential make it an invaluable resource for the development of novel drugs with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 23100-12-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,1,0 and 0 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 23100-12:
(7*2)+(6*3)+(5*1)+(4*0)+(3*0)+(2*1)+(1*2)=41
41 % 10 = 1
So 23100-12-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H4ClNO/c7-6-2-1-5(4-9)3-8-6/h1-4H
23100-12-1Relevant articles and documents
Practical synthesis of (6-chloro-3-pyridyl)methylamine by highly selective hydrogenation of 6-chloro-3-pyridinecarbonitrile with improved Raney nickel catalyst
Tanaka, Ken,Nagasawa, Minoru,Sakamura, Hideki
, p. 1227 - 1231 (2000)
A practical synthesis of (6-chloro-3-pyridyl)methylamine (1), one of the key intermediates of neo-nicotinoid insecticides, by a highly selective hydrogenation of 6-chloro-3-pyridinecarbonitrile (4) is described. The use of an improved Raney nickel catalyst, prepared from an alloy of low nickel content (Ni 38%, A1 62%) and subjected to heat treatment in water (98 °C, 2 h) after leaching of aluminum, was highly effective for the selective hydrogenation of 4. The hydrogenation of 4 using this catalyst was carried out in EtOH-H2O [6:1 (v/v)] and NH3 at 50 °C and 1.2-1.4 kg cm-2 hydrogen pressure to give 1 in 86% yield and 3-pyridylmethylamine, a dechlorinated by-product, in 2% yield.
Photocatalytic degradation of imidacloprid by phosphotungstic acid supported on a mesoporous sieve MCM-41
Feng, Changgen,Li, Yanzhou,Liu, Xia
experimental part, p. 127 - 132 (2012/03/09)
Solid catalysts consisting of polyoxometalates (POM) namely phosphotungstic acid H3PW12O40 (HPW) supported on a mesoporous sieve MCM-41 have been prepared and characterized by FT-IR, X-ray diffraction, nitrogen adsorption and high resolution transmission electron microscope (HRTEM). The HPW/MCM-41 with different HPW loadings from 10 to 60 wt% possess large specific surface area and rather uniform mesopores. Keggin structure of HPW retains on the prepared composite catalysts. The photocatalytic performance of HPW/MCM-41 was examined by degradation of a durable pesticide imidacloprid. It is found that the prepared photocatalysts exhibit high activity under irradiation of 365 nm monochromatic light. For 50 mL of imidacloprid (10 mg/L), conversion of imidacloprid using 20 mg of HPW/MCM-41 with 50 wt% loading level and calcined at 300°C reaches 58.0% after 5 h irradiation. Copyright
