23938-71-8

Basic information

• Product Name: 3-propanoyldihydrofuran-2(3H)-one
• CAS NO: 23938-71-8
• Molecular Formula: C₇H₁₀O₃
• Molecular Weight: 142.1525
• Mol File: 23938-71-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 293.8°C at 760 mmHg
• Flash Point: 131°C
• Density: 1.146g/cm³
• Vapor Pressure: 0.00169mmHg at 25°C
• Refractive Index: 1.46
• CAS DataBase Reference: 3-propanoyldihydrofuran-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-propanoyldihydrofuran-2(3H)-one(23938-71-8)
• EPA Substance Registry System: 3-propanoyldihydrofuran-2(3H)-one(23938-71-8)

Safety Data

• Hazardous Substances Data: 23938-71-8(Hazardous Substances Data)

Usage

General Description

3-propanoyldihydrofuran-2(3H)-one, also known as acetyl dihydro-2-furanone, is a chemical compound with the molecular formula C7H10O2. It is a colorless liquid with a sweet, caramel-like odor, commonly used in food additives and flavoring agents. 3-propanoyldihydrofuran-2(3H)-one is found naturally in various fruits and is often used to impart a caramel-like flavor to foods and beverages. It is also used in perfumes and cosmetics for its sweet scent and serves as a precursor for the synthesis of various pharmaceuticals and organic compounds. Additionally, it has been studied for its potential antioxidant and antimicrobial properties, making it a versatile and valuable chemical in various industries.

Upstream product

• 96-48-0 4-butanolide 
• 79-03-8 propionyl chloride 
• 554-12-1 propanoic acid methyl ester 
• 105-37-3 Ethyl propionate 

Downstream Products

• 20434-22-4 6-bromo-3-hexanone 
• 112776-53-1 (4-oxohexyl)triphenylphosphonium iodide 
• 96890-24-3 3-(2-ethyl-1,3-dioxolan-2-yl)propyltriphenylphosphonium iodide 
• 1232237-77-2 tert-butyl (S)-((R)-2-oxo-3-propionyltetrahydrofuran-3-yl)(phenyl)methylcarbamate 

Relevant articles and documents

NOVEL SUBSTITUTED CONDENSED PYRIMIDINE COMPOUNDS

Novel substituted condensed pyrimidine compounds of general formula (I) in which the chemical groupings, substituents and indices are as defined in the description, and to their use as medicaments, in particular as medicaments for the treatment of conditions and diseases that can be treated by inhibition of the PDE4 enzyme.

Synthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors

Tumor cells extensively utilize the pentose phosphate pathway for the synthesis of ribose. Transketolase is a key enzyme in this pathway and has been suggested as a target for inhibition in the treatment of cancer. In a pharmacodynamic study, nude mice with xenografted HCT-116 tumors were dosed with 1 ('N3′-pyridyl thiamine'; 3-(6-methyl-2-amino-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium chloride hydrochloride), an analog of thiamine, the co-factor of transketolase. Transketolase activity was almost completely suppressed in blood, spleen, and tumor cells, but there was little effect on the activity of the other thiamine-utilizing enzymes α-ketoglutarate dehydrogenase or glucose-6-phosphate dehydrogenase. Synthesis and SAR of transketolase inhibitors is described.

Synthesis and biological activity substituted of 2-(4-imidazolyl)ethylamines

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